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Comparison of contrast sensitivity, depth of field and ocular wavefront aberrations in eyes with an IOL with zero versus positive spherical aberration

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Abstract

Purpose

To compare the clinical performance of the zero spherical aberration (SA) SofPort LI61AO (AO, Bausch & Lomb) intraocular lens (IOL) to the AcrySof SA60AT (AT, Alcon), which has positive spherical aberration.

Methods

Patients underwent uneventful phacoemulsification with implantation of either an aspheric (AO, n = 19) or spherical (AT, n = 20) IOL. Postoperatively, a 5 mm artificial pupil was positioned in trial frames with the cycloplegic refraction during monocular, mesopic contrast sensitivity (CSF) and low-contrast visual acuity (LCVA) testing with glare. Ocular and corneal wavefront error was determined at 5 mm diameters.

Results

Mean CSF scores were better at all frequencies tested for the AO than for the AT group, and achieved statistical significance at 1.5 cpd (p = 0.038) and 6 cpd (p = 0.017). With glare, AO eyes read 30.9 ± 5.0 low-contrast letters versus 25.2 ± 6.8 for AT eyes (p = 0.005) (mean ΔLogMAR  =  −0.10), while high-contrast acuity and refraction were similar. Eyes implanted with the SA60AT had 43% greater positive spherical aberration at a 5 mm wavefront diameter, with no significant difference in corneal SA between groups. A through-focus analysis demonstrated a similar depth of field, yet a comparatively higher visual Strehl ratio for the aspheric IOL at emmetropia (p = 0.038).

Conclusion

Eyes with the SofPort Advance Optics neutral aberration IOL demonstrated less spherical aberration and better low-contrast acuity compared to eyes with a spherical IOL, without sacrificing tolerance to defocus. The aspheric IOL showed superior optical and clinical performance, which is most likely due to its surface design.

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Authors and Affiliations

  1. Pepose Vision Institute, 1815 Clarkson Road, Chesterfield, MO, 63107, USA

    Jay S. Pepose, Mujtaba A. Qazi & Jeff P. Sanderson

  2. Department of Ophthalmology & Visual Sciences, Washington University School of Medicine. St. Louis, Missouri, USA

    Jay S. Pepose & Mujtaba A. Qazi

  3. Sarver & Associates, Carbondale, Illinois, USA

    Edwin J. Sarver

  4. Bausch & Lomb, Rochester, New York, USA

    Keith H. Edwards

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  1. Jay S. Pepose
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  2. Mujtaba A. Qazi
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  3. Keith H. Edwards
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  4. Jeff P. Sanderson
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  5. Edwin J. Sarver
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Correspondence to Jay S. Pepose.

Additional information

Supported in part by research grants from the Midwest Cornea Foundation, St. Louis, MO, USA and Bausch & Lomb, Rochester, NY, USA. Drs. Pepose, Qazi and Sanderson have no financial interest in the products described. Dr. Pepose has received research and travel support from Bausch & Lomb. Dr. Sarver has a financial interest in the VOL-CT Software used in this study. Mr. Edwards is an employee of Bausch & Lomb. Dr. Pepose is a paid consultant for Bausch & Lomb, Rochester, NY, USA

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Pepose, J.S., Qazi, M.A., Edwards, K.H. et al. Comparison of contrast sensitivity, depth of field and ocular wavefront aberrations in eyes with an IOL with zero versus positive spherical aberration. Graefes Arch Clin Exp Ophthalmol 247, 965–973 (2009). https://doi.org/10.1007/s00417-009-1038-1

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  • DOI: https://doi.org/10.1007/s00417-009-1038-1

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