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A prospective trial of phaco-trabeculotomy combined with deep sclerectomy versus phaco-trabeculectomy

  • Glaucoma
  • Published:
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Abstract

Background

Combined phacoemulsification, intraocular lens implantation, and trabeculectomy (PTE) is currently the standard procedure for most ophthalmic surgeons to treat uncontrolled open-angle glaucoma and cataract at one time. This study was designed to prospectively compare a new technique of phaco-trabeculotomy plus deep sclerectomy (PDSTO) with standard phaco-trabeculectomy (PTE).

Methods

A consecutive series of 43 patients with uncontrolled open-angle glaucoma and cataract underwent combined glaucoma and cataract surgery. The procedure started as a two-site approach with phacoemulsification and IOL implantation through a temporal incision in clear cornea. Trabeculotomy and deep sclerectomy were performed in the superior quadrant. Trabeculectomy was also performed in the superior quadrant as a modified Cairns trabeculectomy. Postoperatively, examinations were performed on a daily base for 1 week. Follow-up visits were applied 1, 3, 6, and 12 months after surgery.

Results

The mean preoperative intraocular pressure (IOP) was 26.5 mmHg (SD 7.8) for all patients enrolled. The mean IOP was 12.3 mmHg (SD 5.1) 1 day post surgery for the PTE group (p < 0.001) and 14.4 mmHg (SD 4.0) for the PDSTO group (p < 0.001). At 12 months post surgery the success rate according to the Advanced Glaucoma Intervention Study (AGIS), defined as an IOP lower than 18mmHg without medication, was 20% in the PTE group and 50% in the PDSTO group (p = 0.03). The number of postoperative complications was equally low for both groups. No severe complications, such as bleb infection, endophthalmitis, or choroidal hemorrhage were seen in this series.

Conclusions

PDSTO offered significant IOP reduction and a success rate which was higher than that of the current standard, PTE. The specific intra- and postoperative complications of deep sclerectomy, trabeculotomy, and trabeculectomy were seen in our series, although the overall rate of postoperative complications proved low.

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Authors and Affiliations

  1. Center of Ophthalmology, University of Cologne, Cologne, Germany

    Christoph Lüke, Thomas S. Dietlein, Walter Konen & Günter K. Krieglstein

  2. Department of Ophthalmology, University of Tübingen, Tübingen, Germany

    Matthias Lüke

  3. Zentrum für Augenheilkunde, Universität Köln, Joseph-Stelzmann Str. 9, 50924, Köln, Germany

    Christoph Lüke

Authors
  1. Christoph Lüke
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  2. Thomas S. Dietlein
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  3. Matthias Lüke
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  4. Walter Konen
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  5. Günter K. Krieglstein
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Correspondence to Christoph Lüke.

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Lüke, C., Dietlein, T.S., Lüke, M. et al. A prospective trial of phaco-trabeculotomy combined with deep sclerectomy versus phaco-trabeculectomy. Graefes Arch Clin Exp Ophthalmol 246, 1163–1168 (2008). https://doi.org/10.1007/s00417-008-0821-8

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  • DOI: https://doi.org/10.1007/s00417-008-0821-8

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