Skip to main content
SpringerLink
Log in

Letter to the editor: confirming neonatal seizure and late onset ataxia in SCN2A Ala263Val

  • Letter to the Editors
  • Published:
Journal of Neurology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Herlenius E, Heron SE, Grinton BE, Keay D, Scheffer IE, Mulley JC, Berkovic SF (2007) SCN2A mutations and benign familial neonatal-infantile seizures: the phenotypic spectrum. Epilepsia 48:1138–1142

    Article  CAS  PubMed  Google Scholar 

  2. Liao Y, Anttonen AK, Liukkonen E, Gaily E, Maljevic S, Schubert S, Bellan-Koch A, Petrou S, Ahonen VE, Lerche H, Lehesjoki AE (2010) SCN2A mutation associated with neonatal epilepsy, late-onset episodic ataxia, myoclonus, and pain. Neurology 75:1454–1458

    Article  CAS  PubMed  Google Scholar 

  3. Liao Y, Deprez L, Maljevic S, Pitsch J, Claes L, Hristova D, Jordanova A, Ala-Mello S, Bellan-Koch A, Blazevic D, Schubert S, Thomas EA, Petrou S, Becker AJ, De Jonghe P, Lerche H (2010) Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy. Brain 133:1403–1414

    Article  PubMed  Google Scholar 

  4. Schwarz N, Hahn A, Bast T, Muller S, Loffler H, Maljevic S, Gaily E, Prehl I, Biskup S, Joensuu T, Lehesjoki AE, Neubauer BA, Lerche H, Hedrich UB (2016) Mutations in the sodium channel gene SCN2A cause neonatal epilepsy with late-onset episodic ataxia. J Neurol 263:334–343

    Article  CAS  PubMed  Google Scholar 

  5. Yu FH, Catterall WA (2003) Overview of the voltage-gated sodium channel family. Genome Biol 4:207

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Danish Epilepsy Centre, Filadelfia, 4293, Dianalund, Denmark

    Katrine M. Johannesen & Rikke S. Møller

  2. Institute of Regional Health Services, University of Southern Denmark, Odense, Denmark

    Katrine M. Johannesen & Rikke S. Møller

  3. Department of Pediatrics, Herlev University Hospital, University of Copenhagen, Herlev, Denmark

    Maria J. Miranda

  4. Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

    Holger Lerche

Authors
  1. Katrine M. Johannesen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Maria J. Miranda
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Holger Lerche
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Rikke S. Møller
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Katrine M. Johannesen.

Ethics declarations

Conflicts of interest

The authors declare no conflicts of interest.

Ethical standard

This study was approved by the ethical committee of Western Zealand, Denmark. Parents provided informed written consent to publish clinical data and videos.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Video 1, 2 and 3: Photage of an episode of ataxia. Filmed by parents. Parents have provided consent for publication

Supplementary material 1 (MP4 190569 kb)

Supplementary material 2 (MP4 201580 kb)

Supplementary material 3 (MP4 147152 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Johannesen, K.M., Miranda, M.J., Lerche, H. et al. Letter to the editor: confirming neonatal seizure and late onset ataxia in SCN2A Ala263Val. J Neurol 263, 1459–1460 (2016). https://doi.org/10.1007/s00415-016-8149-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-016-8149-5

Keywords

Search

Navigation