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Chromosome 22q11.2 deletion syndrome: an underestimated cause of neuropsychiatric impairment in adolescence

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References

  1. Yagi H, Furutani Y, Sasaki T, Asakawa S, Minoshima S, Ichida F, Joo K, Kimura M, Imamura S, Kamatami N, Momma K, Takao A, Nakazawa M, Shimizu N, Matsuoka R (2003) Role of TBX1 in human del 22q11. 2 syndrome. Lancet 362(9393):1342–1343

    Article  Google Scholar 

  2. Scambler PJ, Carey AH, Wyse RK, et al. (1991) Microdeletions within 22q11 associated with sporadic and familial Di George syndrome. Genomics 10:201–206

    Article  PubMed  Google Scholar 

  3. Scambler PJ, Kelly D, Lindsay E, et al. (1992) Velocardiofacial syndrome associated with chromosome 22 deletions encompassing the Di George locus. Lancet 339:1138–1139

    Article  PubMed  Google Scholar 

  4. Perez E, Sullivan K (2002) Chromosome 22q11. 2 deletion syndrome (Di George and velocardiofacial syndromes). Curr Opin Pediatr 14:678–683

    Article  PubMed  Google Scholar 

  5. Mc Donald–Mc, Ginn DM, Kirschner R, Goldmuntz E, et al. (1999) The Philadelphia story: the 22q11. 2 deletion: report on 250 patients. Genet Couns 10:11–24

    PubMed  Google Scholar 

  6. Pulver AE, Nestadt G, Goldberg R, Shprintzen R, Lamacz M, Wolyniec P, Morrow B, Karayiorgou M, Antonarakis S, Housman D, Kucherpalati R (1994) Psychotic illness in patients diagnosed with velocardiofacial syndrome and their relatives. J Nerv Ment Dis 182:476–478

    PubMed  Google Scholar 

  7. Murphy KC, Jones LA, Owen MJ (1999) High rates of schizophrenia in adults with velocardiofacial syndrome. Arch Gen Psychiatry 56:940–945

    PubMed  Google Scholar 

  8. Papolos D, Faedda G, Veit S, Goldberg R, Morrow B, Kucherpalati R, Shprintzen RJ (1996) Bipolar spectrum disorders in patients diagnosed with velocardiofacial syndrome: does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder. Am J Psychiatry 153:1541–1547

    PubMed  Google Scholar 

  9. Kao A, Mariani J, Mc Donald Mc Ginn DM, Maisenbacher MK, Brooks–Kayal AR, Zackai EH, Lynch DR (2004) Increased prevalence of unprovoked seizures in patients with a 22q11. 2 deletion. Am J Med Genet 129A(1): 29–34

    Article  Google Scholar 

  10. Kates WR, Burnette CP, Jabs EW, Rutberg J, Murphy AM, Grados M, Geraghty M, Kaufmann WE, Pearlson GD (2001) Regional cortical white matter reductions in velocardiofacial syndrome: a volumetric MRI analysis. Biol Psychiatry 49(8):677–684

    PubMed  Google Scholar 

  11. Barnea–Goraly N, Menon V, Krasnow B, Ko A, Reiss A, Eliez S (2003) Investigation of white matter structure in velocardiofacial syndrome: a diffuse tensor imaging study. Am J Psychiatry 160(10):1863–1869

    Article  PubMed  Google Scholar 

  12. Kawame H, Adachi M, Tachibana K, et al. (2001) Grave’s disease in patients with 22q11. 2 deletion. J Pediatr 139:892–895

    Article  PubMed  Google Scholar 

  13. Lawrence S, Mc Donald–Mc Ginn DM, Zackai E, Sullivan KE (2003) Thrombocytopenia in patients with chromosome 22q11. 2 deletion syndrome. J Pediatr 143(2):277–278

    Article  PubMed  Google Scholar 

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Parissis, D., Milonas, I. Chromosome 22q11.2 deletion syndrome: an underestimated cause of neuropsychiatric impairment in adolescence. J Neurol 252, 989–990 (2005). https://doi.org/10.1007/s00415-005-0788-x

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  • DOI: https://doi.org/10.1007/s00415-005-0788-x

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