Abstract
Insertion/null polymorphisms (INNULs) can be used as an alternative marker of STRs to detect the highly degraded samples in forensic cases. In this study, we evaluated the genetic data of 20 INNUL markers in the Innotyper® 21 Human DNA Analysis Kit (InnoGenomics) for Hainan Li population, including allele frequencies and forensic parameters. No significant deviation from Hardy-Weinberg equilibrium and linkage disequilibrium was found in all loci after Bonferroni correction. The combined power of discrimination (CPD) was 0.99999891, the combined power of exclusion for duo paternity testing (CPEduo) was 0.75274389, and the combined power of exclusion for trio paternity testing (CPEtrio) was 0.94766143. These data would be useful for the application of the kit in practice and the research of the kit used in molecular anthropology studies.
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All procedures performed in the study involving human participants were in accordance with the ethical standards of the Medical Ethics Committee of Hebei Medical University (No. 2018011) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Xu, J., Sun, L., Wang, X. et al. Population data for 20 insertion-null allele markers in the Li ethnic minority from Hainan Province. Int J Legal Med 134, 2075–2077 (2020). https://doi.org/10.1007/s00414-020-02424-8
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DOI: https://doi.org/10.1007/s00414-020-02424-8