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Genetic characterization of 19 X-STRs in Sierra Leone population from Freetown

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Abstract

A total of 550 individuals (265 males and 285 females) from Sierra Leone, a west-African coastal country, were genotyped using the Microreader™ 19X ID System kit. No significant deviations from the Hardy-Weinberg equilibrium were observed. A total of 250 alleles were identified with corresponding allele frequencies spanning from 0.0012 to 0.6762. PIC of the loci ranged from 0.4615 to 0.9481. The CPE, CPDF, and CPDM were 0.9999997856, 0.999999999999999999995774, and 0.999999999998997, respectively. The highly combined MECKruger, MECKishida, MECDesmarais, and MECDesmarais Duo were achieved as 0.99999992508, 0.999999999990802, 0.999999999990836, and 0.99999998412, respectively. Genetic comparisons revealed that genetic homogeneity existed in similar ethno origin or geographic origin populations. This is a pioneering genetic investigation using the Microreader™ 19X ID System kit in the population of Sierra Leone.

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Acknowledgments

This study was financially supported by the National Natural Science Foundation of China (NSFC, no. 81871533), Natural Science Foundation of Hunan Province (2017JJ3422), Postdoctoral Science Foundation of Central South University (229795), and Shanghai Key Laboratory of Forensic Medicine Open Project (KF1815).

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Author notes

  1. Lin Lin and Jienan Li contributed equally to this work.

Authors and Affiliations

  1. Xiangya Hospital, Central South University, No87. Xiangya Road, Changsha, Hunan, People’s Republic of China

    Lin Lin

  2. Reproductive Medicine Center, Fujian Provincial Maternity and Children’s Hospital, No18. Daoshan Road, Fuzhou, Fujian, People’s Republic of China

    Lin Lin

  3. Department of Forensic Science, School of Basic Medical Sciences, Central South University, No172. Tongzipo Road, Changsha, 410013, Hunan Province, People’s Republic of China

    Jienan Li, Aliye Kureshi, Chudong Wang, Moutanou Modeste Judes Zeye & Lagabaiyila Zha

  4. Wuxi Municipal Public Security Bureau, Wuxi, Jiangsu, People’s Republic of China

    Yize Hu

  5. Department of Clinical Diagnostic Centre, the Fifth Medical Centre, Chinese PLA (People’s Liberation Army) General Hospital, Beijing, People’s Republic of China

    Han Wang

  6. The GREY Bush Community Health Center, Grey Bush, Ascension-town, Sierra Leone

    Foday Ambrose Marah

  7. Joint Medical Unit, Freetown, Sierra Leone

    Moses Moseray

  8. Clinical Laboratory, 34 Military hospital, Freetown, Sierra Leone

    Moses Moseray

  9. Laboratory of Molecular Biology and Genetics (LMBG), University Joseph KI – ZERBO, CERBA/LABIOGENE, 01 BP 364, Ouagadougou 01, Burkina Faso

    Moutanou Modeste Judes Zeye

  10. China-Africa Research Center of Infectious Deseases, Central South University, Changsha, People’s Republic of China

    Lagabaiyila Zha

Authors
  1. Lin Lin
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  2. Jienan Li
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  3. Yize Hu
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  4. Han Wang
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  5. Foday Ambrose Marah
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  6. Moses Moseray
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  7. Aliye Kureshi
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  8. Chudong Wang
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  9. Moutanou Modeste Judes Zeye
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  10. Lagabaiyila Zha
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Corresponding author

Correspondence to Lagabaiyila Zha.

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Our experiments were approved by the Ethics Committee of The Grey Bush Community Health Center, Ascension-town, Sierra Leone.

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The authors declare that they have no conflict of interest.

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Lin, L., Li, J., Hu, Y. et al. Genetic characterization of 19 X-STRs in Sierra Leone population from Freetown. Int J Legal Med 134, 1659–1661 (2020). https://doi.org/10.1007/s00414-019-02243-6

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  • DOI: https://doi.org/10.1007/s00414-019-02243-6

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