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Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual “Headcheese Pattern” with Nodules

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Abstract

A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.

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References

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Authors and Affiliations

  1. Department of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy

    V. Pietrangeli, S. Tomassetti, C. Ravaglia, C. Gurioli, Ch. Gurioli & V. Poletti

  2. Servizio Pneumologico Territoriale, Azienda Sanitaria dell’Alto Adige, Bolzano, Italy

    V. Pietrangeli

  3. Department of Radiology, Ospedale GB Morgagni, Forlì, Italy

    S. Piciucchi

  4. Department of Pathology, Arcispedale S. Maria Nuova/I.R.C.C.S., Reggio Emilia, Italy

    A. Cavazza

  5. Department of Pathology, Ospedale GB Morgagni, Forlì, Italy

    A. Dubini

  6. Department of Respiratory Diseases & Allergology, Aarhus University Hospital, Aarhus, Denmark

    V. Poletti

Authors
  1. V. Pietrangeli
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  2. S. Piciucchi
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  3. S. Tomassetti
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  4. C. Ravaglia
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  5. C. Gurioli
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  6. Ch. Gurioli
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  7. A. Cavazza
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  8. A. Dubini
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  9. V. Poletti
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Corresponding author

Correspondence to S. Piciucchi.

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Pietrangeli, V., Piciucchi, S., Tomassetti, S. et al. Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual “Headcheese Pattern” with Nodules. Lung 193, 1051–1054 (2015). https://doi.org/10.1007/s00408-015-9817-4

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  • DOI: https://doi.org/10.1007/s00408-015-9817-4

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