Abstract
Nasal septum deviation (NSD) can cause obstruction of the upper airway, which may lead to increased pulmonary artery pressure (PAP) and right ventricle dysfunction. The aim of the present study was to evaluate the effect of septoplasty on right ventricular function and mean PAP of patients with marked NSD. 25 patients with marked NSD (mean age = 31.8 ± 12.3 years) and 27 healthy volunteers (mean age = 34.5 ± 10.8 years) were enrolled. Echocardiography was performed for all subjects and right ventricular function and mean PAP were evaluated before and 3 months after septoplasty. Tricuspid annular plane systolic excursion (TAPSE) and tricuspid annulus early diastolic myocardial velocity (E′) were significantly lower in patients with NSD than control subjects, while right ventricle myocardial performance index (RVMPI) and mean PAP were significantly higher (respectively, p = 0.006, 0.037, 0.049, 0.046). When preoperative and postoperative findings were compared, the mean PAP decreased whereas TAPSE increased significantly (respectively, p = 0.007, 0.03). The results of the present study demonstrated that mean PAP increased and right ventricular function worsened in patients with NSD. However, mean PAP decreased and right ventricular function tended to recover after septoplasty.
Similar content being viewed by others
References
Gray LP (1978) Deviated nasal septum: incidence and etiology. Ann Otol Rhinol Laryngol 87:3–20
Yilmaz MD, Onrat E, Altuntaz A, Kaya D, Kahveci OK, Ozel O, Dereköy S, Celik A (2005) The effects of tonsillectomy and adenoidectomy on pulmonary arterial pressure in children. Am J Otolaryngol 26:18–21
McNicholas WT (2009) Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med 180:692–700. doi:10.1164/rccm.200903-0347PP
Naiboglu B, Deveci S, Duman D, Kaya KS, Toros S, Kinis V, Sürmeli M, Deveci I, Gokceer T (2008) Effect of upper airway obstruction on pulmonary arterial pressure in children. Int J Pediatr Otorhinolaryngol 72:1425–1429. doi:10.1016/j.ijporl.2008.06.005
Yonker AJ, Spaur RC (1987) Upper airway obstruction. Otolaryngol Clin North Am 20:235–239
Fidan V, Aksakal E (2011) Impact of septoplasty on pulmonary artery pressure in patients with markedly deviated septum. J Craniofac Surg 22:1591–1593. doi:10.1097/SCS.0b013e31822e5e21
Hassanpour SE, Moosavizadeh SM, Fadaei Araghi M, Eshraghi B (2014) Pulmonary artery pressure in patients with markedly deviated septum candidate for septorhinoplasty. World J Plast Surg 3:119–121
Sciller NB, Shah PM, Crawford M et al (1989) Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. The American Society of Echocardiography Committee on Standards. Subcommittee on quantitation of two-dimensional echocardiograms. J Am Soc Echocardiogr 2:358–367
Isobe M, Yazaki Y, Takaku F, Koizumi K, Hara K, Tsuneyoshi H, Yamaguchi T, Machii K (1986) Prediction of pulmonary arterial pressure in adults by pulsed Doppler echocardiography. Am J Cardiol 57:316–321
Dabestani A, Mahan G, Gardin JM, Takenaka K, Burn C, Allfie A, Henry WL (1987) Evaluation of pulmonary artery pressure and resistance by pulsed Doppler echocardiography. Am J Cardiol 59:662–668
Levy AM, Tabakin BS, Hanson JS, Narkewicz RM (1967) Hypertrophied adenoids causing pulmonary hypertension and severe cardiac failure. N Engl J Med 77:506–511
Duman D, Naiboglu B, Esen HS, Toros SZ, Demirtunc R (2008) Impaired right ventricular function in adenotonsillar hypertrophy. Int J Cardiovasc Imaging 24:261–267
Dursunoglu N, Dursunoglu D (2005) The effects of obstructive sleep apnea hypopnea syndrome on cardiovascular system. Anatol J Cardiol 5:41–45 (in Turkish)
Sandoval J, Bauerle O, Palomar A, Gómez A, Martínez-Guerra ML, Beltrán M, Guerrero ML (1994) Survival in primary pulmonary hypertension. Validation of a prognostic equation. Circulation 89:1733–1744
Çetin M, Yılmaz M, Özen S, Bozan N, Coşkun Ş (2014) Assessment of pulmonary artery pressure and right ventricular function in children with adenotonsillar hypertrophy using different parameters. Int J Pediatr Otorhinolaryngol 78:1837–1842. doi:10.1016/j.ijporl.2014.08.003
García-Fernández MA, Azevedo J, Moreno M, Bermejo J, Pérez-Castellano N, Puerta P, Desco M, Antoranz C, Serrano JA, García E, Delcán JL (1999) Regional diastolic function in ischemic heart disease using pulsed wave Doppler tissue imaging. Eur Heart J 20:496–505
Yu CM, Sanderson JE, Marwick TH, Oh JK (2007) Tissue Doppler imaging a new prognosticator for cardiovascular diseases. J Am Coll Cardiol 49:1903–1914
Moustapha A, Lim M, Saikia S, Kaushik V, Kang SH, Barasch E (2001) Interrogation of the tricuspid annulus by Doppler tissue imaging in patients with chronic pulmonary hypertension: implications for the assessment of right-ventricular systolic and diastolic function. Cardiology 95:101–104
Ugur MB, Dogan SM, Sogut A, Uzun L, Cinar F, Altin R, Aydin M (2008) Effect of adenoidectomy and/or tonsillectomy on cardiac functions in children with obstructive sleep apnea. ORL J Otorhinolaryngol Relat Spec 70:202–208
Koc S, Aytekin M, Kalay N, Ozcetin M, Burucu T, Ozbek K, Celik A, Kadi H, Gulturk S, Koc F (2012) The effect of adenotonsillectomy on right ventricle function and pulmonary artery pressure in children with adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 76:45–48. doi:10.1016/j.ijporl.2011.09.028
Portnoy SG, Rudski LG (2015) Echocardiographic evaluation of the right ventricle: a 2014 perspective. Curr Cardiol Rep 17:21
El-Damarawy M, Zeidan H, Suwailem S (2008) Myocardial performance index in patients with chronic obstructive pulmonary disease. Heart Mirror J 2:60–66
Blanchard DG, Malouf PJ, Gurudevan SV, Auger WR, Madani MM, Thistlethwaite P, Waltman TJ, Daniels LB, Raisinghani AB, DeMaria AN (2009) Utility of right ventricular Tei index in the noninvasive evaluation of chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy. JACC Cardiovasc Imaging 2:143–149. doi:10.1016/j.jcmg.2008.10.012
Tekten T, Onbasili AO, Ceyhan C, Unal S, Discigil B (2003) Novel approach to measure myocardial performance index: pulsed-wave tissue Doppler echocardiography. Echocardiography 20:503–510
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
The Ethics Committee of the Afyon Kocatepe University School of Medicine approved this study. All patients and control subjects gave informed consent prior to inclusion
Conflict of interest
All authors declared that there was no conflict of interest.
Funding
No financial support was received for this study. It was conducted with the dedication of researchers.
Rights and permissions
About this article
Cite this article
Ozkececi, G., Akci, O., Bucak, A. et al. The effect of septoplasty on pulmonary artery pressure and right ventricular function in nasal septum deviation. Eur Arch Otorhinolaryngol 273, 3747–3752 (2016). https://doi.org/10.1007/s00405-016-4042-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00405-016-4042-1