Abstract
The aim of this study was to evaluate the functional outcome of facial nerve repair with fibrin glue in end-to-end anastomosis and intermediate nerve graft. Thirty-six patients undergoing facial nerve repair by end–to-end anastomosis or facial nerve grafting using exclusively fibrin glue between 1986 and 1999 were included in this retrospective study. The population comprised ten vestibular schwannomas (28%), nine temporal bone fractures (25%), seven facial nerve schwannomas (19%), four facial nerve hemangiomas (11%), two iatrogenic facial nerve interruptions (6%) and four miscellaneous facial nerve lesions (11%). Data were reviewed concerning etiology, location of the nerve interruption, type of repair and postoperative facial function according to the repaired facial nerve recovery scale (A: normal; B: independent movements of eyelid and mouth; C: strong closure of eyelids and mouth; D: incomplete eyelid closure; E: minimal movement; F: no movement). Eleven patients (31%) underwent end-to-end nerve anastomosis and 25 (69%) underwent intermediate facial nerve grafting. The mean follow-up period was 50 months (range: 3–95). Among patients followed-up more than 18 months (n=20), a score of B or C was obtained in 16 patients (80%), a score D in 2 cases (10%) and a score E in 2 cases (10%). The type of repair and the site of interruption did not influence the results. Fibrin glue is a simple, rapid and efficient means of facial nerve repair. In case of intraoperative facial nerve interruption, this type of repair can be attempted in any location at the time of the tumor removal.
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May M (2000) Nerve repair. In: May M, Shaitkin BM (eds) The facial nerve, 2nd edn. Theime, New York, pp 571–609
Egloff DV, Narakas A (1983) Nerve anastomosis with human fibrin. Preliminary clinical report (56 cases). Ann Chir Main 2:101–115
Maragh H, Meyer BS, Davenport D, Gould JD, Terzis JK (1990) Morphofunctional evaluation of fibrin glue versus microsuture nerve repairs. J Reconstr Microsurg 6:331–337
Bento RF, Miniti A (1993) Anastomosis of the intratemporal facial nerve using fibrin tissue adhesive. ENT J 72:663–672
Sterkers O, Badr El Dine M, Bagot d’Arc M, Tedaldi R, Sterkers JM (1990) Fibrin glue anastomosis of the facial nerve in the cerebello-pontine angle, the petrous bone, and the parotid: 60 cases. Rev Laryngol 111:433–435
House JW, Brackmann DE (1985) Facial nerve grading system. Otolaryngol Head Neck Surg 3:184–193
Committee on Hearing and Equilibrium guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma) (1995) Otolaryngol Head Neck Surg 113:179–180
Gidley PW, Gantz BJ, Rubinstein JT (1999) Facial nerve grafts: from cerebellopontine angle and beyond. Am J Otol 20:781–788
Medders G, Mattox DE, Lyles A (1989) Effects of fibrin glue on rat facial nerve regeneration. Otolaryngol Head Neck Surg 100:106–109
Bento RF, Miniti A (1989) Comparison between fibrin tissue adhesive, epineural suture and natural union in intratemporal facial nerve of cats. Acta Otolaryngol (Suppl) 465:1–36
Menovsky T, Beek JF (2001) Laser, fibrin glue, or suture repair of peripheral nerves: a comparative functionnal, histological, and morphometric study in the rat sciatic nerve. J Neurosurg 95:694–699
Prevel CD, Eppley BL, McCarty M, Brock C (1994) Mechanical anastomosis of nerves: a histological and functional comparison to conventional suturing. Ann Plast Surg 33:600–605
Bascom DA, Schaitkin BM, May M, Klein S (2000) Facial nerve repair: a retrospective review. Facial Plast Surg 16:309–313
Saeed SR, Ramsden RT (1996) Rehabilitation of the paralysed face: results of facial nerve surgery. J Laryngol Otol 110:922–925
Green JD Jr., Shelton C, Brackmann DE (1994) Surgical management of facial nerve injuries. Otolaryngol Head Neck Surg 111:606–610
Steinert EI (1979) Hypoglossofacial anastomosis: its significance for modern facial surgery II. Combined approach in extratemporal facial nerve reconstruction. Clin Plast Surg 6:471–486
Moy OJ, Peimer CA, Koniuch MP, Howard C, Zielezny M, Katikaneni PR (1988) Fibrin seal adhesive versus nonresorbable microsuture in peripheral nerve repair. J Hand Surg 13:273–278
Hamm KD, Steube D, Pothe H, Beer R (1988) Experimental studies in animals on the use of a fibrin glue from the human plasma fraction Cohn I in nerve reconstruction. Folia Haematol Int Mag Klin Morphol Bluforrsch 115:208–212
Myles LM, Gilmour JA, Glasby MA (1992) Effects of different methods of peripheral nerve repair on the number and distribution of muscle afferent neurons in rat dorsal root ganglion. J Neurosurg 73:457–462
Spector JG (1985) Mimetic surgery for the paralyzed face. Laryngoscope 95:1494–1522
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Bozorg Grayeli, A., Mosnier, I., Julien, N. et al. Long-term functional outcome in facial nerve graft by fibrin glue in the temporal bone and cerebellopontine angle. Eur Arch Otorhinolaryngol 262, 404–407 (2005). https://doi.org/10.1007/s00405-004-0829-6
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DOI: https://doi.org/10.1007/s00405-004-0829-6