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Is there any correlation between amh and obesity in premenopausal women?

  • General Gynecology
  • Published:
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Abstract

Purpose

To evaluate the correlation between the levels of anti-mullerian hormone and body mass index between obese and non-obese premenopausal women.

Methods

Serum anti-mullerian hormone levels of women younger than 45 years admitted to our reproductive endocrinology clinic for investigation of infertility were examined in this cross-sectional study. Body mass indices were lower than 30 kg/m2 in 222 patients and equal to or higher than 30 kg/m2 in 37 patients. Levels of antimullerian hormone were analyzed in each group. Blood samples obtained from study subjects were assayed for levels of anti-mullerian hormone, follicle-stimulating hormone, luteinizing hormone, estradiol, prolactin and thyroid stimulating hormone.

Results

There was no significant difference in terms of mean age between the two groups. There was no statistically significant difference between these two groups in terms of FSH, LH, estradiol and prolactin levels. Anti-mullerian hormone levels were 3.46 ± 2.79 ng/ml and 3.79 ± 2.93 ng/ml in non-obese and obese participants, respectively. No statistically significant correlation was found between Anti Müllerian Hormone (AMH) levels and BMI levels in either group (P > 0.05).

Conclusions

Body mass index does not have an effect on serum AMH levels in women of reproductive age. Obesity has no association with levels of serum follicle stimulating hormone, luteinizing hormone, estradiol, prolactin and thyroid stimulating hormone. Obesity is unlikely to affect ovarian reserve in the premenopausal age group.

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Conflict of interest

Authors declare no conflicts of interest.

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Authors and Affiliations

  1. Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Cerrahpaşa School of Medicine, Istanbul University, Istanbul, Turkey

    Sezai Sahmay, Cemal Tamer Erel, Metehan İmamoğlu, Mustafa Küçük, Nil Atakul & Hakan Seyisoğlu

  2. Department of Obstetrics and Gynecology, Bagcilar Education and Research Hospital, Bagcilar, Istanbul, Turkey

    Taner Usta

Authors
  1. Sezai Sahmay
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  2. Taner Usta
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  3. Cemal Tamer Erel
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  4. Metehan İmamoğlu
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  5. Mustafa Küçük
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  6. Nil Atakul
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  7. Hakan Seyisoğlu
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Correspondence to Taner Usta.

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Sahmay, S., Usta, T., Erel, C.T. et al. Is there any correlation between amh and obesity in premenopausal women?. Arch Gynecol Obstet 286, 661–665 (2012). https://doi.org/10.1007/s00404-012-2363-x

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  • DOI: https://doi.org/10.1007/s00404-012-2363-x

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