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Pain levels associated with renal colic and primary dysmenorrhea: a prospective controlled study with objective and subjective outcomes

  • General Gynecology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objectives

To evaluate the degree of pain associated with renal colic and primary dysmenorrhea using objective and subjective measurements.

Methods

In total, 60 subjects participated in this study. There were 20 subjects in the renal colic group (average age 24.45 ± 2.35 years), 20 subjects in the primary dysmenorrhea group (average age 23.75 ± 1.86 years), and 20 subjects in the control group (average age 24.20 ± 2.57 years). The serum chromogranin A (CgA) values were determined by an enzyme-linked immunosorbent assay and the mean pain score was assessed by means of a Visual Analog Scale (VAS) for each individual.

Results

The serum CgA level was 19.83 ± 19.61 ng/ml for the renal colic group, 13.45 ± 8.52 ng/ml for the primary dysmenorrhea group and 12.45 ± 7.76 ng/ml for the control group. The mean VAS score for pain was 7.95 ± 1.54 for the renal colic group and 7.05 ± 1.50 for the primary dysmenorrhea group.

Conclusions

Primary dysmenorrheic pain is as intense as renal colic pain. Emergency room physicians should display the same degree of care and attention for the treatment of patients with primary dysmenorrhea as they do for patients with renal colic, and rapidly initiate an effective treatment for these patients.

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References

  1. Jones AE (2004) Managing the pain of primary and secondary dysmenorrhoea. Nurs Times 100:40–43

    PubMed  Google Scholar 

  2. Ma YX, Ma LX, Liu XL, Ma YX, Lv K, Wang D et al (2010) A comparative study on the immediate effects of electroacupuncture at Sanyinjiao (SP6), Xuanzhong (GB39) and a non-meridian point, on menstrual pain and uterine arterial blood flow, in primary dysmenorrhea patients. Pain Med 11:1564–1575

    Article  PubMed  Google Scholar 

  3. Coco AS (1999) Primary dysmenorrhea. Am Fam Physician 60:489–496

    PubMed  CAS  Google Scholar 

  4. Holdgate A, Pollock T (2005) Nonsteroidal anti-inflammatory drugs (NSAIDs) versus opioids for acute renal colic. Cochrane Database Syst Rev (2):CD004137

  5. Davenport K, Timoney AG, Keeley FX (2005) Conventional and alternative methods for providing analgesia in renal colic. BJU Int 95:297–300

    Article  PubMed  Google Scholar 

  6. Bektas F, Eken C, Karadeniz O, Goksu E, Cubuk M, Cete Y (2009) Intravenous paracetamol or morphine for the treatment of renal colic: a randomized, placebo-controlled trial. Ann Emerg Med 54:568–574

    Article  PubMed  Google Scholar 

  7. d’Herbomez M, Do Cao C, Vezzosi D, Borzon-Chasot F, Baudin E, Groupe des tumeurs endocrines (GTE France) (2010) Chromogranin A assay in clinical practice. Ann Endocrinol (Paris) 71:274–280

    Article  Google Scholar 

  8. Hamaguchi T, Fukudo S, Kanazawa M, Tomiie T, Shimizu K, Oyama M et al (2008) Changes in salivary physiological stress markers induced by muscle stretching in patients with irritable bowel syndrome. Biopsychosoc Med 4(2):20

    Article  Google Scholar 

  9. Kanegane K, Penha SS, Munhoz CD, Rocha RG (2009) Dental anxiety and salivary cortisol levels before urgent dental care. J Oral Sci 51:515–520

    Article  PubMed  Google Scholar 

  10. Toda M, Den R, Nagasawa S, Kitamura K, Morimoto K (2005) Relationship between lifestyle scores and salivary stress markers cortisol and chromogranin A. Arch Environ Occup Health 60:266–269

    Article  PubMed  CAS  Google Scholar 

  11. Jones KR, Vojir CP, Hutt E, Fink R (2007) Determining mild, moderate, and severe pain equivalency across pain-intensity tools in nursing home residents. J Rehabil Res Dev 44:305–314

    Article  PubMed  Google Scholar 

  12. Erdine S (2004) Pain relief as a human right, global day against pain: IASP and EFIC initiative cosponsored by WHO, 11th October. Geneva. 16:5–8

    Google Scholar 

  13. Heavner JE (2001) Anesthesia update: agents, definitions, and strategies. Comp Med 51:500–503

    PubMed  CAS  Google Scholar 

  14. Unsal A, Ayranci U, Tozun M, Arslan G, Calik E (2010) Prevalence of dysmenorrhea and its effect on quality of life among a group of female university students. Ups J Med Sci 115:138–145

    Article  PubMed  Google Scholar 

  15. Rapkin AJ (1996) Pelvic pain and dysmenorrhea. In: Berek JS, Adashi EY, Hillard PA (eds) Novak’s gynecology. Williams & Wilkins, Baltimore, pp 403–404

    Google Scholar 

  16. Kelly AM (2000) Nurse-managed analgesia for renal colic pain in the emergency department. Aust Health Rev 23:185–189

    Article  PubMed  CAS  Google Scholar 

  17. Muslumanoglu AY, Binbay M, Yuruk E, Akman T, Tepeler A, Esen T et al (2011) Updated epidemiologic study of urolithiasis in Turkey. I: Changing characteristics of urolithiasis. Urol Res 39:309–314

    Article  PubMed  Google Scholar 

  18. Larroy C (2002) Comparing visual-analog and numeric scales for assessing menstrual pain. Behav Med 27:179–181

    Article  PubMed  Google Scholar 

  19. Downie WW, Leatham PA, Rhind VM, Wright V, Branco JA, Anderson JA (1978) Studies with pain rating scales. Ann Rheum Dis 37:378–381

    Article  PubMed  CAS  Google Scholar 

  20. Liu CZ, Xie JP, Wang LP, Zheng YY, Ma ZB, Yang H et al (2011) Immediate analgesia effect of single point acupuncture in primary dysmenorrhea: a randomized controlled trial. Pain Med. 12:300–307

    Article  PubMed  Google Scholar 

  21. Grissa MH, Claessens YE, Bouida W, Boubaker H, Boudhib L, Kerkeni W et al (2011) Paracetamol vs piroxicam to relieve pain in renal colic. Results of a randomized controlled trial. Am J Emerg Med 29:203–206

    Article  PubMed  Google Scholar 

  22. Mortelmans LJ, Desruelles D, Baert JA, Hente KR, Tailly GG (2006) Use of tramadol drip in controlling renal colic pain. J Endourol 20:1010–1015

    Article  PubMed  Google Scholar 

  23. Cohen E, Hafner R, Rotenberg Z, Fadilla M, Garty M (1998) Comparison of ketorolac and diclofenac in the treatment of renal colic. Eur J Clin Pharmacol 54:455–458

    Article  PubMed  CAS  Google Scholar 

  24. Kheirollahi AR, Tehrani M, Bashashati M (2010) A comparison of the effect of intranasal desmopressin and intramuscular hyoscine N-butyl bromide combination with intramuscular hyoscine N-butyl bromide alone in acute renal colic. J Res Med Sci. 15:214–218

    PubMed  CAS  Google Scholar 

  25. Kudielka BM, Buske-Kirschbaum A, Hellhammer DH, Kirschbaum C (2004) Differential heart rate reactivity and recovery after psychosocial stress (TSST) in healthy children, younger adults, and elderly adults: the impact of age and gender. Int J Behav Med. 11:116–121

    Article  PubMed  Google Scholar 

  26. Toda M, Morimoto K (2008) Effect of lavender aroma on salivary endocrinological stress markers. Arch Oral Biol 53:964–968

    Article  PubMed  CAS  Google Scholar 

  27. Akiyoshi H, Aoki M, Shimada T, Noda K, Kumagai D, Saleh N et al (2005) Measurement of plasma chromogranin A concentrations for assessment of stress responses in dogs with insulin-induced hypoglycemia. Am J Vet Res 66:1830–1835

    Article  PubMed  CAS  Google Scholar 

  28. Miyakawa M, Matsui T, Kishikawa H, Murayama R, Uchiyama I, Itoh T et al (2006) Salivary chromogranin A as a measure of stress response to noise. Noise Health. 8:108–113

    Article  PubMed  Google Scholar 

  29. Den R, Toda M, Ohira M, Morimoto K (2011) Levels of awakening salivary CgA in response to stress in healthy subjects. Environ Health Prev Med 16:155–157

    Article  PubMed  CAS  Google Scholar 

  30. Noto Y, Kudo M, Hirota K (2010) Back massage therapy promotes psychological relaxation and an increase in salivary chromogranin A release. J Anesth. 24:955–958

    Article  PubMed  Google Scholar 

  31. Filaire E, Dreux B, Massart A, Nourrit B, Rama LM, Teixeira A (2009) Salivary alpha-amylase, cortisol and chromogranin A responses to a lecture: impact of sex. Eur J Appl Physiol 106:71–77

    Article  PubMed  CAS  Google Scholar 

  32. Seki-Nakamura K, Maebayashi K, Nasu-Izumi S, Akimoto T, Mitsuhashi N (2011) Evaluation of anxiety and salivary chromogranin a secretion in women receiving breast conserving surgery followed by radiation therapy. J Radiat Res (Tokyo). 52:351–359

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Emergency Medicine, Faculty of Medicine, Gazıosmanpaşa University, Tokat, Turkey

    Murat Ayan

  2. Department of Biochemistry, Faculty of Medicine, Gazıosmanpaşa University, Tokat, Turkey

    Erkan Sogut & Mehmet Sahin

  3. Department of Anatomy, Faculty of Medicine, Gazıosmanpaşa University, Tokat, Turkey

    Ufuk Tas

  4. Department of Urology, Faculty of Medicine, Gazıosmanpaşa University, Tokat, Turkey

    Fikret Erdemir

  5. Department of Anesthesiology and Reanimation, Faculty of Medicine, Gazıosmanpaşa University, Tokat, Turkey

    Mustafa Suren & Ziya Kaya

  6. Department of Obstetrics and Gynecology, Faculty of Medicine, Gazıosmanpaşa University, Tokat, Turkey

    Fazlı Demirturk

Authors
  1. Murat Ayan
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  2. Erkan Sogut
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  4. Fikret Erdemir
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Correspondence to Murat Ayan.

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Ayan, M., Sogut, E., Tas, U. et al. Pain levels associated with renal colic and primary dysmenorrhea: a prospective controlled study with objective and subjective outcomes. Arch Gynecol Obstet 286, 403–409 (2012). https://doi.org/10.1007/s00404-012-2316-4

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  • DOI: https://doi.org/10.1007/s00404-012-2316-4

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