Skip to main content

Advertisement

Log in

Primary leiomyosarcoma of broad ligament: case report and review of literature

  • Case Report
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

Introduction

Primary leiomyosarcoma of the broad ligament (LBL) is a very rare and highly malignant gynecological tumor.

Materials and methods

A 45 year old hysterectomized woman with this rare tumor is presented. Treatment consisted of resection of the tumor along with omental and peritoneal sampling and adjuvant chemotherapy. No evidence of metastasis was present after 15 months of follow up.

Conclusion

Complete surgery along with adjuvant chemotherapy or radiation and a close follow up for recurrence are advocated to optimize disease free survival.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Gardner GH, Greene RR, Peckham R (1957) Tumors of the broad ligament. Am J Obstet Gynecol 73:536–555

    PubMed  CAS  Google Scholar 

  2. Lowell DM, Karsh J (1968) Leiomyosarcoma of the broad ligament. A case report. Obstet Gynecol 32:107–110

    PubMed  CAS  Google Scholar 

  3. Ullman AS, Roumell TL (1973) A case report. Leiomyosarcoma of the broad ligament. Mich Med 72:411–414

    Google Scholar 

  4. Weed JC Jr, Podger K (1976) Leiomyosarcoma of the broad ligament coincident with ductal carcinoma of the breast. South Med J 69(10):1379–1380

    PubMed  Google Scholar 

  5. DiDomenico A, Stangl F, Bennington J (1982) Leiomyosarcoma of the broad ligament. Gynecol Oncol 13(3):412–415. doi:10.1016/0090-8258(82)90080-4

    Article  CAS  Google Scholar 

  6. Raj Kumar G (1982) Leiomyosarcoma of probable ovarian or broad ligament origin. Br J Obstet Gynaecol 89(4):327–329

    PubMed  CAS  Google Scholar 

  7. Herbold D, Fu Y, Silbert S (1983) Leiomyosarcoma of the broad ligament. A case report and literature review with follow up. Am J Surg Pathol 7(3):285–292. doi:10.1097/00000478-198304000-00007

    Article  PubMed  CAS  Google Scholar 

  8. Shimm DS, McDonough JF (1987) Leiomyosarcoma of the broad ligament: report of a case. Gynecol Oncol 26(1):123–126. doi:10.1016/0090-8258(87)90079-5

    Article  PubMed  CAS  Google Scholar 

  9. Lee JF, Yang YC, Lee YN et al (1991) Leiomyosarcoma of the broad ligament—report of two cases. Chin Med J 48:59–65

    CAS  Google Scholar 

  10. Cheng WF, Lin HH, Chen CK et al (1995) Leiomyosarcoma of the broad ligament: a case report and literature review. Gynecol Oncol 56(1):85–89. doi:10.1006/gyno.1995.1014

    Article  PubMed  CAS  Google Scholar 

  11. Pekin T, Eren F, Pekin O (2000) Leiomyosarcoma of the broad ligament: case report and literature review. Eur J Gynaecol Oncol 21(3):318–319

    PubMed  CAS  Google Scholar 

  12. Shah A, Finn C, Light A (2003) Leiomyosarcoma of the broad ligament: a case report and literature review. Gynecol Oncol 90(2):450–452. doi:10.1016/S0090-8258(03)00208-7

    Article  PubMed  CAS  Google Scholar 

  13. Agarwal U, Dahiya P, Sangwan K (2003) Leiomyosarcoma of the broad ligament mimicking as ovarian carcinoma—a case report. Arch Gynecol Obstet 269(1):55–56. doi:10.1007/s00404-002-0418-0

    Article  PubMed  Google Scholar 

  14. El Idrissi F, Fadli A (2004) Leiomyosarcoma of the broad ligament. Presse Med 33(15):1004–1005. doi:10.1016/S0755-4982(04)98823-9

    Article  PubMed  Google Scholar 

  15. Murialdo R, Usset A, Guido T et al (2005) Leiomyosarcoma of the broad ligament: a case report and review of literature. Int J Gynecol Cancer 15(6):1226–1229. doi:10.1111/j.1525-1438.2005.00176.x

    Article  PubMed  CAS  Google Scholar 

  16. Ben AF, Jouini H, Nasr M et al (2007) Primary leiomyosarcoma of broad ligament. Tunis Med 85(7):591–595

    Google Scholar 

  17. Zaloudek C, Michael RH (2004) Mesenchymal tumours of the uterus. In: Kurman RJ (ed) Blaustein’s Pathology of the female genital tract, 5th edn. Springer, New York, pp 561–615

    Google Scholar 

  18. Coindre JM, Nguyen BB, Bonichon F et al (1988) Histopathologic grading in spindle cell soft tissue sarcomas. Cancer 61(11):2305–2309. doi:10.1002/1097-0142(19880601)61:11<2305::AID-CNCR2820611126>3.0.CO;2-M

    Article  PubMed  CAS  Google Scholar 

  19. Eltabbakh GH (2007) Broad ligament lipoma presenting as a pelvic mass: a case report. J Reprod Med 52(6):543–544

    PubMed  Google Scholar 

  20. Cobellis L, Pecori E, Rigatti F et al (2007) A rare case of female pelvic mass: angioleiomyoma of the broad ligament. Eur Gynecol Oncol 28(5):418–420

    CAS  Google Scholar 

  21. Zubor P, Kajo K, Szunyogh N et al (2007) A solitary fibrous tumor in the broad ligament of the uterus. Pathol Res Pract 203(7):555–560. doi:10.1016/j.prp.2007.02.005

    Article  PubMed  Google Scholar 

  22. Kir G, Eren S, Akoz I et al (2003) Leiomyosarcoma of the broad ligament arising in a pre-existing pure neurilemmoma-like leiomyoma. Eur J Gynaecol Oncol 24(6):505–506

    PubMed  CAS  Google Scholar 

  23. Jahier H, Gares R, Ganeval C (1958) Recurrent leiomyosarcoma of the left broad ligament. Bull Fed Soc Gynecol Obstet Lang Fr 10(2):167–168

    PubMed  CAS  Google Scholar 

  24. Zeloudex C, Brenda WN (2006) The ovary and fallopian tube. In: Silverberg SG, Delellis RA, Frable WJ et al (eds) Silverberg’s principles and practice of surgical pathology and cytopathology, 4th edn. Churchill Livingstone, Philadelphia, pp 1987–2062

    Google Scholar 

  25. Gadducci A, Cosio S, Romanini A et al (2008) The management of patients with uterine sarcoma: a debated clinical challenge. Crit Rev Oncol Hematol 65(2):129–142. doi:10.1016/j.critrevonc.2007.06.011

    Article  PubMed  Google Scholar 

  26. Scurry JP, Sumithran E (1989) An assessment of the value of frozen sections in gynecological surgery. Pathology 21(3):159–163. doi:10.3109/00313028909061051

    Article  PubMed  CAS  Google Scholar 

  27. Hensley ML, Blessing JA, Mannel R, Rose PG (2008) Fixed-dose rate gemcitabine plus docetaxel as first-line therapy for metastatic uterine leiomyosarcoma: a Gynecologic Oncology Group phase II trial. Gynecol Oncol 109(3):329–334. doi:10.1016/j.ygyno.2008.03.010

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nirmala Duhan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Duhan, N., Singh, S., Kadian, Y.S. et al. Primary leiomyosarcoma of broad ligament: case report and review of literature. Arch Gynecol Obstet 279, 705–708 (2009). https://doi.org/10.1007/s00404-008-0777-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-008-0777-2

Keywords

Navigation