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Adenocarcinoma in situ coexisting with carcinoma in situ of the cervix during pregnancy

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Abstract

Case report

We report a pregnant patient with adenocarcinoma in situ (AIS) coexisting with carcinoma in situ (CIS) of the cervix diagnosed by conization at 16 weeks' gestation. Apoptotic activity was higher in the CIS lesion than in the AIS lesion in the cone biopsy specimen. Postpartum evaluation confirmed the disappearance of CIS lesion with positive cone margins, however, multifocal AIS with negative cone margins was found.

Conclusion

Clinical course and biological features of AIS associated with pregnancy may be different from those of CIS.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Shimane Medical University, 693-8501, Izumo, Japan

    Miwa Nagaishi, Ritsuto Fujiwaki, Kohkichi Hata & Kohji Miyazaki

  2. Department of Obstetrics and Gynecology, Gohtsu Saiseikai General Hospital, Gohtsu, Japan

    Ken Makihara & Yoshio Yamane

Authors
  1. Miwa Nagaishi
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  2. Ritsuto Fujiwaki
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  3. Kohkichi Hata
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  4. Ken Makihara
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  5. Yoshio Yamane
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  6. Kohji Miyazaki
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Corresponding author

Correspondence to Ritsuto Fujiwaki.

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Nagaishi, M., Fujiwaki, R., Hata, K. et al. Adenocarcinoma in situ coexisting with carcinoma in situ of the cervix during pregnancy. Arch Gynecol Obstet 270, 116–118 (2004). https://doi.org/10.1007/s00404-002-0469-2

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  • DOI: https://doi.org/10.1007/s00404-002-0469-2

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