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Variant allelic frequency of driver mutations predicts success of genomic DNA methylation classification in central nervous system tumors

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Fig. 1

Data availability

All data shown in this manuscript is available in Supplementary Table S1.

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Acknowledgements

The authors wish to thank the faculty members of the Neuropathology Division and the faculty and staff of the Molecular Pathology Division at Northwestern University and New York University for their assistance in identifying cases and facilitating data collection.

Funding

CH was supported by NIH under Grant Nos. R01NS102669, R01NS117104, and R01NS118039, the Northwestern University SPORE in Brain Cancer P50CA221747, and the Lou and Jean Malnati Brain Tumor Institute. MM was supported by the NIH under Grant No. F32CA264883.

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Authors and Affiliations

  1. Department of Pathology, Feinberg School of Medicine, Northwestern University, 303 E Superior Street, 6-518, Chicago, IL, 60611, USA

    Pouya Jamshidi, Matthew McCord, Lucas Santana-Santos, Lawrence J. Jennings & Craig Horbinski

  2. Department of Neurological SurgeryFeinberg School of Medicine, Northwestern University, Chicago, USA

    Craig Horbinski

  3. Department of Pathology, New York University, Langone Health, New York, USA

    Kristyn Galbraith & Matija Snuderl

Authors
  1. Pouya Jamshidi
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  2. Matthew McCord
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  3. Kristyn Galbraith
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  4. Lucas Santana-Santos
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  5. Lawrence J. Jennings
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  6. Matija Snuderl
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  7. Craig Horbinski
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Contributions

PJ and CH designed the project. PJ, MM, KG, MS, and CH identified cases and performed data collection. PJ, MM, LS, KG, LJ, MS, and CH organized and processed data, and generated figures. CH, LJ, LS, and MS supervised the project. CH provided financial support. PJ, MM, LS, LJ, and CH drafted the manuscript. All co-authors reviewed and edited the manuscript.

Corresponding author

Correspondence to Craig Horbinski.

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Conflict of interest

C.H. is a member of the Editorial Board of Acta Neuropathologica but was not involved in the Editorial handling of this article. The remaining authors declare no potential conflict of interest.

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Jamshidi, P., McCord, M., Galbraith, K. et al. Variant allelic frequency of driver mutations predicts success of genomic DNA methylation classification in central nervous system tumors. Acta Neuropathol 145, 365–367 (2023). https://doi.org/10.1007/s00401-023-02542-8

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  • DOI: https://doi.org/10.1007/s00401-023-02542-8

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