References
Braggio E, Van Wier S, Ojha J et al (2015) Genome-wide analysis uncovers novel recurrent alterations in primary central nervous system lymphomas. Clin Cancer Res. doi:10.1158/1078-0432.CCR-14-2116
Bruno A, Boisselier B, Labreche K, Marie Y, Polivka M, Jouvet A, Adam C, Figarella-Branger D, Miquel C, Eimer S, Houillier C, Soussain C, Mokhtari K, Daveau R, Hoang-Xuan K (2014) Mutational analysis of primary central nervous system lymphoma. Oncotarget 5:5065–5075
Heidenreich B, Rachakonda PS, Hemminki K, Kumar R (2014) TERT promoter mutations in cancer development. Curr Opin Genet Dev 24:30–37. doi:10.1016/j.gde.2013.11.005
Hoang-Xuan K, Bessell E, Bromberg J et al (2015) Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology. Lancet Oncol 16:e322–e332. doi:10.1016/S1470-2045(15)00076-5
Koelsche C, Sahm F, Capper D et al (2013) Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system. Acta Neuropathol (Berl) 126:907–915. doi:10.1007/s00401-013-1195-5
Labussière M, Di Stefano AL, Gleize V et al (2014) TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations. Br J Cancer 111:2024–2032. doi:10.1038/bjc.2014.538
Laigle-Donadey F, Martin-Duverneuil N, Lejeune J, Crinière E, Capelle L, Duffau H, Cornu P, Broët P, Kujas M, Mokhtari K, Carpentier A, Sanson M, Hoang-Xuan K, Thillet J, Delattre JY (2004) Correlations between molecular profile and radiologic pattern in oligodendroglial tumors. Neurology 63:2360–2362. doi:10.1212/01.WNL.0000148642.26985.68
Li Y, Tergaonkar V (2014) Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies. Cancer Res 74:1639–1644. doi:10.1158/0008-5472.CAN-13-3568
Sturm D, Witt H, Hovestadt V et al (2012) Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22:425–437. doi:10.1016/j.ccr.2012.08.024
Vater I, Montesinos-Rongen M, Schlesner M et al (2015) The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing. Leukemia 29:677–685. doi:10.1038/leu.2014.264
Acknowledgments
This work is part of the national program Cartes d’Identité des Tumeurs® (CIT) funded and developed by the Ligue nationale contre le cancer. This study was supported by Lymphomes Oculo-Cérébraux (LOC) study group network (réseau national de centres experts des lymphomes primitifs du système nerveux central, Institut National du Cancer), Association pour la recherche sur les tumeurs cérébrales (ARTC), Ligue nationale contre le cancer (Comité du Val d’Oise, R14044DD), Fondation pour la Recherche Médicale (FDT20140930968) and program “Investissements d’avenir” ANR-10-IAIHU-06.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Bruno, A., Alentorn, A., Daniau, M. et al. TERT promoter mutations in primary central nervous system lymphoma are associated with spatial distribution in the splenium. Acta Neuropathol 130, 439–440 (2015). https://doi.org/10.1007/s00401-015-1461-9
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00401-015-1461-9