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Social determinants of colorectal cancer risk, stage, and survival: a systematic review

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Abstract

Background

Several social determinants of health have been examined in relation to colorectal cancer incidence, stage at diagnosis, and survival including income, education, neighborhood disadvantage, immigration status, social support, and social network. Colorectal cancer incidence rates are positively associated with income and other measures of socioeconomic status. In contrast, low socioeconomic status tends to be associated with poorer survival.

Methods

The present review is based upon bibliographic searches in PubMed and CINAHL and relevant search terms. Articles published in English from 1970 through April 1, 2019 were identified using the following MeSH search terms and Boolean algebra commands: colorectal cancer AND (incidence OR stage OR mortality) AND (social determinants OR neighborhood disadvantage OR racial discrimination OR immigration OR social support).

Results

This review indicates that poverty, lack of education, immigration status, lack of social support, and social isolation play important roles in colorectal cancer stage at diagnosis and survival.

Conclusions

To address social determinants of colorectal cancer, effective interventions are needed that account for the social contexts in which patients live.

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Authors and Affiliations

  1. Department of Population Health Sciences, Medical College of Georgia, Augusta University, 1120 15th Street, Augusta, GA, 3091, USA

    Steven S. Coughlin

  2. Institute of Public and Preventive Health, Augusta University, Augusta, GA, USA

    Steven S. Coughlin

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Correspondence to Steven S. Coughlin.

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Coughlin, S.S. Social determinants of colorectal cancer risk, stage, and survival: a systematic review. Int J Colorectal Dis 35, 985–995 (2020). https://doi.org/10.1007/s00384-020-03585-z

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