Skip to main content
Log in

One- versus two-stage single-incision laparoscopic cyst excision and hepaticojejunostomy in patients with completely perforated choledochal cysts and good medical conditions

  • Original Article
  • Published:
Pediatric Surgery International Aims and scope Submit manuscript

Abstract

Background

The aim of the current study was to evaluate the efficacy of one- and two-stage single-incision laparoscopic hepaticojejunostomy (SILH) for perforated CDCs with good medical conditions.

Methods

Between June 2015 and December 2020, 57 patients were reviewed: Group 1: patients who underwent one-stage SILH (n = 16); Group 2: patients who underwent two-stage SILH (n = 41). The demographic characteristics, operational details, postoperative outcomes and postoperative complications were evaluated.

Results

The mean follow-up durations of group 1 and 2 were 39.3 and 38.6 months, respectively. One patient (6.3%) in group 1, and 4 patients (9.8%) in group 2 were converted to laparotomy (p = 0.67). No statistical significance was found in operative time, blood transfusion, time to resume full diet, duration of drainage after definitive surgery and postoperative hospital stays between the two groups. Four patients in group 2 developed bile leakage, which was higher than that in group 1 (9.8% vs 0, p = 0.20). None suffered incidental injury, bleeding, anastomotic stenosis, cholangitis, cholelithiasis, pancreatic leakage, pancreatitis, Roux-loop obstruction, adhesive intestinal obstruction or wound infection. Liver function normalized within 1 year postoperatively in both groups.

Conclusions

In experienced hands, one-stage single-incision laparoscopic hepaticojejunostomy is safe and effective for patients with complete perforations and good medical conditions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Nguyen Thanh L, Hien PD, Dung LA, Son TN (2010) Laparoscopic repair for choledochal cyst: lessons learned from 190 cases. J Pediatr Surg 45(3):540–544. https://doi.org/10.1016/j.jpedsurg.2009.08.013

    Article  PubMed  Google Scholar 

  2. Diao M, Li L, Cheng W (2018) Single-incision laparoscopic hepaticojejunostomy for children with perforated choledochal cysts. Surg Endosc 32(7):3402–3409. https://doi.org/10.1007/s00464-018-6047-x

    Article  PubMed  Google Scholar 

  3. Diao M, Li L, Cheng W (2020) Timing of choledochal cyst perforation. Hepatology 71(2):753–756. https://doi.org/10.1002/hep.30902

    Article  PubMed  Google Scholar 

  4. Diao M, Li L, Cheng W (2013) Single-incision laparoscopic hepaticojejunostomy using conventional instruments for neonates with extrahepatic biliary cystic lesions. Surg Innov 20(3):214–218. https://doi.org/10.1177/1553350612446355

    Article  PubMed  Google Scholar 

  5. Horaguchi J, Fujita N, Kobayashi G, Noda Y, Ito K, Takasawa O (2005) Clinical study of choledochocele: is it a risk factor for biliary malignancies? J Gastroenterol 40(4):396–401. https://doi.org/10.1007/s00535-005-1554-7

    Article  PubMed  Google Scholar 

  6. Stringer MD, Dhawan A, Davenport M, Mieli-Vergani G, Mowat AP, Howard ER (1995) Choledochal cysts: lessons from a 20 year experience. Arch Dis Child 73(6):528–531

    Article  CAS  Google Scholar 

  7. Ando K, Miyano T, Kohno S, Takamizawa S, Lane G (1998) Spontaneous perforation of choledochal cyst: a study of 13 cases. Eur J Pediatr 8(1):23–25

    Article  CAS  Google Scholar 

  8. Fukuzawa H, Urushihara N, Miyakoshi C, Kajihara K, Kawahara I, Isono K, Samejima Y, Miura S, Uemura K, Morita K, Nakao M, Yokoi A, Fukumoto K, Yamoto M, Maeda K (2018) Clinical features and risk factors of bile duct perforation associated with pediatric congenital biliary dilatation. Pediatr Surg Int 34(10):1079–1086. https://doi.org/10.1007/s00383-018-4321-6

    Article  PubMed  Google Scholar 

  9. Ando H, Ito T, Watanabe Y, Seo T, Kaneko K, Nagaya M (1995) Spontaneous perforation of choledochal cyst. J Am Coll Surg 181(2):125–128

    CAS  PubMed  Google Scholar 

  10. Xin Y, Wang XM, Wang Y, Hu YX, Jia LQ (2020) Value of ultrasound in diagnosing perforation of congenital choledochal cysts in children. J Ultrasound Med. https://doi.org/10.1002/jum.15604

    Article  PubMed  Google Scholar 

  11. Mishra A, Pant N, Chadha R, Choudhury SR (2007) Choledochal cysts in infancy and childhood. Indian J Pediatr 74(10):937–943

    Article  Google Scholar 

  12. Sai Prasad TR, Chui CH, Low Y, Chong CL, Jacobsen AS (2006) Bile duct perforation in children: is it truly spontaneous? Ann Acad Med Singap 35(12):905–908

    CAS  PubMed  Google Scholar 

  13. Minagawa T, Dowaki S, Kikunaga H, Fujita K, Ishikawa K, Mori K, Sakuragawa T, Ichisaka S, Miura H, Kumai K, Mikami S, Kitagawa Y (2015) Endoscopic biliary drainage as a bridging procedure to single-stage surgery for perforated choledochal cyst: a case report and review of the literature. Surg Case Rep 1(1):117. https://doi.org/10.1186/s40792-015-0115-4

    Article  PubMed  PubMed Central  Google Scholar 

  14. Song G, Mou Y, Ren C, Zhou H, Wang J (2021) Comparison and selection of three methods of minimally invasive external drainage for children with congenital choledochal cysts. J Laparoendosc Adv Surg Tech A 31(4):462–467. https://doi.org/10.1089/lap.2020.0222

    Article  PubMed  Google Scholar 

  15. Ngoc Son T, Thanh Liem N, Manh Hoan V (2014) One-staged or two-staged surgery for perforated choledochal cyst with bile peritonitis in children? A single center experience with 27 cases. Pediatr Surg Int 30(3):287–290. https://doi.org/10.1007/s00383-014-3461-6

    Article  PubMed  Google Scholar 

  16. Wang X, Gao K, Yan C, Guo C (2020) Short- and intermediate-term evaluation of the initial definitive operation for perforated choledochal cysts compared to two-stage management. Eur J Trauma Emerg Surg. https://doi.org/10.1007/s00068-020-01553-4

    Article  PubMed  PubMed Central  Google Scholar 

  17. Yamashita Y, Takada T, Strasberg SM, Pitt HA, Gouma DJ, Garden OJ, Büchler MW, Gomi H, Dervenis C, Windsor JA, Kim S-W, de Santibanes E, Padbury R, Chen X-P, Chan ACW, Fan S-T, Jagannath P, Mayumi T, Yoshida M, Miura F, Tsuyuguchi T, Itoi T, Supe AN (2013) TG13 surgical management of acute cholecystitis. J Hepatobiliary Pancreat Sci 20(1):89–96. https://doi.org/10.1007/s00534-012-0567-x

    Article  PubMed  Google Scholar 

  18. Diao M, Li L, Cheng W (2016) Laparoscopic redo hepaticojejunostomy for children with choledochal cysts. Surg Endosc 30(12):5513–5519. https://doi.org/10.1007/s00464-016-4915-9

    Article  PubMed  Google Scholar 

  19. Nennstiel S, Weber A, Frick G, Haller B, Meining A, Schmid RM, Neu B (2015) Drainage-related complications in percutaneous transhepatic biliary drainage: an analysis over 10 years. J Clin Gastroenterol 49(9):764–770. https://doi.org/10.1097/MCG.0000000000000275

    Article  PubMed  Google Scholar 

  20. Kang CM, Lee KH, Kim DH, Lee WJ (2008) Percutaneous transhepatic cyst drainage as a “bridge procedure” to definitive treatment of perforated choledochal cysts: a case report. Surg Laparosc Endosc Percutan Tech 18(6):598–600. https://doi.org/10.1097/SLE.0b013e31818096a0

    Article  PubMed  Google Scholar 

  21. Wang X, Yu W-L, Fu X-H, Zhu B, Zhao T, Zhang Y-J (2020) Early versus delayed surgical repair and referral for patients with bile duct injury: a systematic review and meta-analysis. Ann Surg 271(3):449–459. https://doi.org/10.1097/SLA.0000000000003448

    Article  PubMed  Google Scholar 

  22. Kim JH, Choi TY, Han JH, Yoo BM, Kim JH, Hong J, Kim MW, Kim WH (2008) Risk factors of postoperative anastomotic stricture after excision of choledochal cysts with hepaticojejunostomy. J Gastrointest Surg 12(5):822–828. https://doi.org/10.1007/s11605-007-0415-5

    Article  PubMed  Google Scholar 

Download references

Funding

The project is supported by The Special Fund of The Pediatric Medical Coordinated Development Center of Beijing Hospitals Authority, No. XTZD20180304.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Long Li or Mei Diao.

Ethics declarations

Conflict of interest

No authors report any conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yin, T., Chen, S., Li, L. et al. One- versus two-stage single-incision laparoscopic cyst excision and hepaticojejunostomy in patients with completely perforated choledochal cysts and good medical conditions. Pediatr Surg Int 38, 541–545 (2022). https://doi.org/10.1007/s00383-022-05073-7

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00383-022-05073-7

Keywords

Navigation