Skip to main content
Log in

The impact of post-operative opioid guidelines on prescribing behaviors in the pediatric population

  • Original Article
  • Published:
Pediatric Surgery International Aims and scope Submit manuscript

Abstract

Background

Opioid misuse continues to be a major source of morbidity and mortality in the US, in both the adult and pediatric populations. Post-operative opioid prescriptions are often the first exposure children have to opioids and increases their risk of chronic use. There is significant variation in the number of opioids following identical procedures and measures have been taken within the adult population to limit this. However, specific post-operative opioid prescription guidelines are not present in the pediatric population.

Methods

Seven common pediatric surgery procedures were selected for inclusion. The recommended number of opioid doses following each procedure was determined by a multi-disciplinary expert panel. All surgery residents were sent an initial survey to determine the number of opioids they would prescribe for each procedure. They were then shown the guidelines and the survey repeated to determine changes in response.

Results

35 and 27 general surgery residents took part in and pre- and post-educational surveys respectively. In all procedures, there was a decrease in the mean number of post-operative opioids prescribed. In addition, there was an increase in the number of residents who prescribed within the guidelines and a decrease in the number who overprescribed post-operative opioids.

Conclusion

Pediatric postoperative opioid prescribing guidelines derived from expert opinion increase resident compliance with appropriate dosing; this has the potential to decrease the classic problem of general surgery residents accustomed to treating adults overprescribing opioids to children. These results are promising, and we aim to expand on this work and incorporate these guidelines into our clinical practice.

Level of evidence

III/IV.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Hedegaard H, Miniño AM, Warner M (2018) Drug overdose deaths in the United States, 1999–2017. NCHS Data Brief 329:1–8

    Google Scholar 

  2. National Institute on Drug Abuse. Overdose Death Rates, 2019. https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates Accessed 11 June 2019

  3. Kane JM, Colvin JD, Bartlett AH et al (2018) Opioid-related critical care resource use in US children’s hospitals. Pediatrics. https://doi.org/10.1542/peds.2017,3335Epub 2018 Mar 5

    Article  PubMed  Google Scholar 

  4. Harbaugh CM, Lee JS, Hu HM et al (2018) Persistent opioid use among pediatric patients after surgery. Pediatrics. https://doi.org/10.1542/peds.2017,2439Epub 2017 Dec 4

    Article  PubMed  Google Scholar 

  5. Chung CP, Callahan ST, Cooper WO et al (2018) Outpatient opioid prescriptions for children and opioid-related adverse events. Pediatrics. https://doi.org/10.1542/peds.2017Epub 2018 Jul 16

    Article  PubMed  PubMed Central  Google Scholar 

  6. Sun EC, Darnall BD, Baker LC et al (2016) Incidence of and risk factors for chronic opioid use among opioid-naive patients in the postoperative period. JAMA Intern Med 176:1286–1293

    Article  Google Scholar 

  7. Hill MV, McMahon ML, Stucke RS et al (2017) Wide variation and excessive dosage of opioid prescriptions for common general surgical procedures. Ann Surg 265:709–714

    Article  Google Scholar 

  8. Makary MA, Overton HN, Wang P (2017) Overprescribing is major contributor to opioid crisis. BMJ 359:j4792

    Article  Google Scholar 

  9. Horton JD, Munawar S, Corrigan C et al (2018) Inconsistent and excessive opioid prescribing after common pediatric surgical operations. J Pet Surg 54:1427–1431

    Article  Google Scholar 

  10. Chen EY, Marcantonio A, Tornetta P (2018) 3rd. Correlation between 24-hour predischarge opioid use and amount of opioids prescribed at hospital discharge. JAMA Surg 153:174859

    Article  Google Scholar 

  11. Hill MV, Stucke RS, McMahon ML et al (2018) An educational intervention decreases opioid prescribing after general surgical operations. Ann Surg 267:468–472

    Article  Google Scholar 

  12. Overton HM, Hanna MN, Bruhn WE et al (2018) Opioid-prescribing guidelines for common surgical procedures: an expert panel consensus. J Am Colle Surg 227(4):411–418

    Article  Google Scholar 

  13. Boulkedid R, Abdoul H, Loustau M et al (2011) Using and reporting the Delphi method for selecting healthcare quality indicators: a systematic review. PLoS ONE 6:e20476

    Article  CAS  Google Scholar 

  14. Gaither JR, Leventhal JM, Ryan SA et al (2016) National trends in hospitalizations for opioid poisonings among children and adolescents, 1997 to 2012. JAMA Pediatr 170:1195–1201

    Article  Google Scholar 

  15. McCabe SE, Teter CJ, Boyd CJ et al (2018) Sources of prescription medication misuse among young adults in the united states: the role of educational status. J Clin Psychiatry. https://doi.org/10.4088/jcp.17m11958

    Article  PubMed  PubMed Central  Google Scholar 

  16. McCabe SE, West BT, Boyd CJ (2013) Leftover prescription opioids and nonmedical use among high school seniors: a multi-cohort national study. J Adolesc Health 52:480–485

    Article  Google Scholar 

  17. Harbaugh CM, Gadepalli SK (2019) Pediatric postoperative opioid prescribing and the opioid crisis. Curr Opin Pediatr 31:378–385

    Article  Google Scholar 

  18. Chatterjee A, Larochelle MR, Xuan Z et al (2019) Non-fatal opioid-related overdoses among adolescents in Massachusetts 2012–2014. Drug Alcohol Depend 194:28–31

    Article  Google Scholar 

  19. Monitto CL, Hsu A, Gao S et al (2017) Opioid prescribing for the treatment of acute pain in children on hospital discharge. Anesth Analg 125:2113–2122

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Eric B. Jelin.

Ethics declarations

Conflict of interest

The authors have no conflict of interest to declare.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Appendix

Appendix

See Tables 1, 2, 3

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Irfan, A., Martin, L.Y., Canner, J. et al. The impact of post-operative opioid guidelines on prescribing behaviors in the pediatric population. Pediatr Surg Int 36, 1339–1343 (2020). https://doi.org/10.1007/s00383-020-04739-4

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00383-020-04739-4

Keywords

Navigation