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Pediatric intracranial aneurysms: changes from previous studies

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Abstract

Purpose

To develop a better understanding of pediatric intracranial aneurysms (PIAs).

Methods

All PIAs treated in our center from January 2012 to April 2017 were retrospectively included. Clinical data, treatment summaries, and follow-up outcomes were retrieved and analyzed.

Results

A total of 66 PIAs were found in 64 patients with a mean age of 11.4 ± 5.7 years, 68.8% of whom were male. The most common symptoms were seizure (n = 7, 63.6%) for the 0–5 age group and headache (n = 38, 71.7%) for the 6–18 age group. Fifty-one PIAs (77.3%) were located in the anterior circulation, with the middle cerebral artery (MCA) being the most common site (n = 28, 42.4%). Fifteen patients (23.4%) had PIAs that were pseudoaneurysms, and nine of them (60%) had a combined history of head trauma. Thirty-five patients (54.7%) had distal arterial aneurysms, and 21 of them (60%) presented with seizure. During a mean follow-up time of 1.6 ± 1.2 years, 79.7% of patients (n = 51) had favorable outcomes, 5 patients (7.8%) died, and the remaining 8 patients (12.5%) had unfavorable outcomes with severe neurological deficits.

Conclusion

Apart from characteristics consistent with previous studies, several new findings regarding PIAs were reported, including a difference in the most common symptoms in different age groups, the MCA as the predominant location of PIAs, the high ratio of pseudoaneurysms and their head trauma etiology, and the incidence of distal arterial aneurysms and their relationship with the risk of seizures.

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Acknowledgments

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Funding

This study was funded by the Fundamental Research Funds for the Central Universities (2012017yjsy200).

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Author notes

  1. Ruiqi Chen and Si Zhang contributed equally to this work.

Authors and Affiliations

  1. Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan, 610041, People’s Republic of China

    Ruiqi Chen, Si Zhang, Chao You, Rui Guo & Lu Ma

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  1. Ruiqi Chen
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  2. Si Zhang
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Correspondence to Lu Ma.

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Chen, R., Zhang, S., You, C. et al. Pediatric intracranial aneurysms: changes from previous studies. Childs Nerv Syst 34, 1697–1704 (2018). https://doi.org/10.1007/s00381-018-3818-6

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