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Ultra early recurrence in giant congenital malignant rhabdoid tumor of spine

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Abstract

Background

Malignant rhabdoid tumor (MRT) is an aggressive tumor of infancy and childhood that rarely presents as a primary spinal or spinal cord tumor. There are only three reported cases of spinal MRT in infants.

Objective

We present a similar case in a 3-month male child who developed ultra-early recurrence, 4 weeks after complete excision. The diagnosis was confirmed by immunohistochemistry showing inactivation of the INI1 gene.

Result

Despite surgical excision and adjuvant chemoradiotherapy, these tumors have a progressive course and recurrence is a common phenomenon.

Conclusion

We believe that MRT must be considered in the differential diagnosis of the intra/paraspinal masses, especially in the infants.

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Abbreviations

MRT:

Malignant rhabdoid tumor

MRI:

Magnetic resonance imaging

ATRT:

Atypical teratoid rhabdoid tumor

EMA:

Epithelial membrane antigen

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, PGIMER Chandigarh, Chandigarh, 160012, India

    Navneet Singla & Ankur Kapoor

  2. Department of Histopathology, PGIMER Chandigarh, Panchkula, India

    Debajyoti Chatterjee & B. D. Radotra

Authors
  1. Navneet Singla
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  2. Ankur Kapoor
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  3. Debajyoti Chatterjee
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  4. B. D. Radotra
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Corresponding author

Correspondence to Ankur Kapoor.

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The parents of the child gave informed consent for submission of the manuscript.

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Singla, N., Kapoor, A., Chatterjee, D. et al. Ultra early recurrence in giant congenital malignant rhabdoid tumor of spine. Childs Nerv Syst 32, 2471–2474 (2016). https://doi.org/10.1007/s00381-016-3178-z

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  • DOI: https://doi.org/10.1007/s00381-016-3178-z

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