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Benign fibrous histiocytoma arising at the temporal bone of an infant—case report and review of the literature

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Abstract

Purpose

We report a very rare case of a fast-growing benign fibrous histiocytoma at the temporal bone.

Methods

A 1-year-old girl was referred for investigation of a right temporal mass that increased during 2-week observation. Imaging studies showed a lytic, loculated skull tumor at the left temporal bone. On magnetic resonance imaging scans, the tumor was isointense on T1- and relatively high-intense on T2-weighted images. The tumor was mostly homogeneously enhanced by gadolinium. On diffusion-weighted images, it was iso- to relatively low-intense; perfusion-weighted images revealed low perfusion.

Results

Complete macroscopic resection of the tumor was performed. Immunohistochemical analysis showed that the tumor was positive for CD68 and α-smooth muscle actin and negative for CD1a and CD34; the MIB-1 labeling index was 4 %. A diagnosis of primary benign fibrous histiocytoma of the skull was made. At 6-month follow-up, there were no clinical or radiological signs of tumor recurrence and/or metastasis.

Conclusions

We review the clinical, radiological, and immunohistochemical characteristics of benign fibrous histiocytoma at the skull.

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Acknowledgments

We thank U. Petralia for the editorial review. This study was partly supported by the Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (C) number 25462262.

Conflict of interest

The authors have no conflicts of interest to disclose.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan

    Fumiyuki Yamasaki, Takeshi Takayasu, Ryo Nosaka, Masako Yoshihiro & Kaoru Kurisu

  2. Department of Pathology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, 734-8551, Japan

    Amatya Jeet Vishwa & Yukio Takeshima

Authors
  1. Fumiyuki Yamasaki
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  2. Takeshi Takayasu
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  3. Ryo Nosaka
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  4. Amatya Jeet Vishwa
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  5. Yukio Takeshima
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  6. Masako Yoshihiro
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  7. Kaoru Kurisu
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Corresponding author

Correspondence to Fumiyuki Yamasaki.

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Yamasaki, F., Takayasu, T., Nosaka, R. et al. Benign fibrous histiocytoma arising at the temporal bone of an infant—case report and review of the literature. Childs Nerv Syst 32, 189–193 (2016). https://doi.org/10.1007/s00381-015-2822-3

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  • DOI: https://doi.org/10.1007/s00381-015-2822-3

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