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High-intensity aerobic interval training can lead to improvement in skeletal muscle power among in-hospital patients with advanced heart failure

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A Correction to this article was published on 20 February 2018

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Abstract

This study investigated the effectiveness and safety of interval training during in-hospital treatment of patients with advanced heart failure. Twenty-four consecutive patients with advanced symptomatic heart failure who were referred for cardiac transplant evaluation were recruited. After performing aerobic exercise for approximate intensity, high-intensity interval training (HIIT) was performed. The protocol consisted of 3 or 4 sessions of 1-min high-intensity exercise aimed at 80% of peak VO2 or 80% heart rate reserve, followed by 4-min recovery periods of low intensity. In addition to the necessary laboratory data, hand grip strength and knee extensor strength were evaluated at the start of exercise training and both at the start and the end of HIIT. Knee extensor strength was standardized by body weight. The BNP level at the start of exercise training was 432 (812) pg/mL and it significantly decreased to 254 (400) pg/mL (p < 0.001) at the end of HIIT. Hand grip strength did not change during course. By contrast, knee extensor strength significantly increased during HIIT [4.42 ± 1.43 → 5.28 ± 1.45 N/kg, p < 0.001], whereas the improvement of knee extensor strength was not significant from the start of exercise training to the start of HIIT. In addition, the change in knee extensor strength during HIIT was significantly associated with the hemoglobin A1c level at the start of exercise (R = − 0.55; p = 0.015). HIIT has a positive impact on skeletal muscle strength among in-hospital patients with advanced heart failure.

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Change history

  • 20 February 2018

    In the original publication of the article, the unit of hand in Fig. 2 was wrongly given as “N/kg” instead of “kg”.

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Acknowledgements

This work was supported by The Ministry of Education, Culture, Sports, Science and Technology of Japan through Grant-in-aid 26,461,103 (to Amiya E).

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Authors and Affiliations

  1. Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan

    Masanobu Taya, Eisuke Amiya, Masaru Hatano, Hisataka Maki, Daisuke Nitta, Akihito Saito, Masaki Tsuji, Yumiko Hosoya, Shun Minatsuki, Atsuko Nakayama, Takayuki Fujiwara, Yuto Konishi, Masafumi Watanabe, Hiroyuki Morita & Issei Komuro

  2. Department of Rehabilitation, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

    Masanobu Taya, Yuto Konishi, Kazuhiko Yokota & Nobuhiko Haga

  3. Department of Therapeutic Strategy for Heart Failure, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

    Masaru Hatano

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  1. Masanobu Taya
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Correspondence to Eisuke Amiya.

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Additional information

The original version of this article was revised: The unit of hand in Fig. 2 was incorrectly published and corrected in this version.

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Taya, M., Amiya, E., Hatano, M. et al. High-intensity aerobic interval training can lead to improvement in skeletal muscle power among in-hospital patients with advanced heart failure. Heart Vessels 33, 752–759 (2018). https://doi.org/10.1007/s00380-018-1120-x

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