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Multiple mechanisms shape selectivity for FM sweep rate and direction in the pallid bat inferior colliculus and auditory cortex

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Abstract

The inferior colliculus and auditory cortex of the pallid bat contain a large percentage of neurons that are highly selective for the direction and rate of the downward frequency modulated (FM) sweep of the bat’s echolocation pulse. Approximately 25% of neurons tuned to the echolocation pulse respond exclusively to downward FM sweeps. This review focuses on the finding that this selectivity is generated by multiple mechanisms that may act alone or in concert. In the inferior colliculus, selectivity for sweep rate is shaped by at least three mechanisms: shortpass or bandpass tuning for signal duration, delayed high-frequency inhibition that prevents responses to slow sweep rates, and asymmetrical facilitation that occurs only when two tones are presented at appropriate delays. When acting alone, the three mechanisms can produce essentially identical rate selectivity. Direction selectivity can be produced by two mechanisms: an early low-frequency inhibition that prevents responses to upward sweeps, and the same asymmetrical two-tone inhibition that shapes rate tuning. All mechanisms except duration tuning are also present in the auditory cortex. Discussion centers on whether these mechanisms are redundant or complementary.

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Abbreviations

FM:

frequency modulated

TTF:

two-tone facilitation

DSI:

direction selectivity index

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Acknowledgments

This review is dedicated to Gerhard Neuweiler. We thank Terri Zumsteg for her assistance with this manuscript. Research was supported by NIH NIDCD Grant DC05202 to ZMF.

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Authors and Affiliations

  1. Department 3166, Zoology and Physiology, University of Wyoming, 1000 E. University Ave, Laramie, WY, 82071, USA

    Zoltan M. Fuzessery, Khaleel A. Razak & Anthony J. Williams

  2. Department of Psychology, University of California, Riverside, CA, 92521, USA

    Khaleel A. Razak

Authors
  1. Zoltan M. Fuzessery
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  2. Khaleel A. Razak
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  3. Anthony J. Williams
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Correspondence to Zoltan M. Fuzessery.

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Fuzessery, Z.M., Razak, K.A. & Williams, A.J. Multiple mechanisms shape selectivity for FM sweep rate and direction in the pallid bat inferior colliculus and auditory cortex. J Comp Physiol A 197, 615–623 (2011). https://doi.org/10.1007/s00359-010-0554-0

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