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Lachsfarbener Bindehauttumor mit Amyloidablagerung

Salmon-pink colored conjunctival tumor with amyloid deposits

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Zusammenfassung

Ein 82-jähriger Patient stellte sich mit einem lachsfarbenen Bindehauttumor am linken Auge vor. Klinisch fiel in der Läsion ein umschriebener, derber, weißlicher Anteil auf. Die histopathologische und immunhistochemische Aufarbeitung des Biopsats ergab ein CD20+-Marginalzonenlymphom der Bindehaut mit Amyloidablagerungen. Extranodale Marginalzonenlymphome sind die häufigsten Lymphome im Bereich der okulären Adnexe und machen dort 5–10% der malignen Erkrankungen aus. Eine assoziierte Amyloidproduktion ist sehr selten und hat nach aktuellem Kenntnisstand keine prognostische Relevanz.

Abstract

An 82-year-old male patient presented with a salmon-pink colored conjunctival tumor of the left eye. A circumscribed, dense and whitish portion was detected by clinical examination. The histophological and immunhistochemical examination of the biopsy tissue revealed a CD20+ marginal zone lymphoma of the conjunctiva with amyloid deposits. Extranodal marginal zone lymphoma at this site is the most common lymphoma of the ocular adnexa and accounts for 5–10% of malignant diseases. An association with amyloid production is very rare and according to the current state of knowledge has no known impact on the outcome.

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Authors and Affiliations

  1. Universitäts-Augenklinik Bonn, Ernst-Abbe-Str. 2, 53127, Bonn, Deutschland

    P.L. Müller, K.U. Loeffler, F.G. Holz & M.C. Herwig

  2. Institut für Pathologie, Universitätsklinikum Bonn, Bonn, Deutschland

    H.-P. Fischer

Authors
  1. P.L. Müller
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  2. K.U. Loeffler
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  3. F.G. Holz
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  4. H.-P. Fischer
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  5. M.C. Herwig
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Correspondence to P.L. Müller.

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P.L. Müller, K.U. Loeffler, F.G. Holz, H.-P. Fischer und M.C. Herwig geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Müller, P., Loeffler, K., Holz, F. et al. Lachsfarbener Bindehauttumor mit Amyloidablagerung. Ophthalmologe 113, 602–605 (2016). https://doi.org/10.1007/s00347-015-0130-7

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  • DOI: https://doi.org/10.1007/s00347-015-0130-7

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