Skip to main content
Log in

Clinical practice guidelines to inform evidence-based clinical practice

  • Topic Paper
  • Published:
World Journal of Urology Aims and scope Submit manuscript

Abstract

Background

With the volume of medical research currently published, any one practitioner cannot independently review the literature to determine best evidence-based medical care. Additionally, non-specialists usually do not have the experience to know best practice for all of the frequent clinical circumstances for which there is no good evidence. Clinical practice guidelines (CPGs) help clinicians to address these problems because they are systematically created documents that summarize knowledge and provide guidance to assist in delivering high-quality medicine. They aim to improve health care by identifying evidence that supports the best clinical care and making clear which practices appear to be ineffective.

Methods

Non-structured literature review.

Results

CPGs combine evidence-based medicine (on topics for which evidence exists) with expert opinion (on topics for which there is no evidence). The optimal CPG applies structured and transparent judgments, from an unbiased and diverse panel which includes both clinical experts and non-physicians, to a systematic evidence review. It includes decisions in areas in which clinical data are both available and unavailable. The resulting guideline statements should be clearly linked to the quality of the available evidence and the target patient(s) should be clearly defined, so that the reader can assess strength and applicability of the statements to an individual patient.

Conclusions

The application of high-quality CPGs improves patient care, but all too often CPGs are not used to the greatest advantage because of inadequate dissemination and incorporation into practice. This article provides an overview of CPGs, focusing on their justification, creation, improvement, and use.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Institute of Medicine (IOM) (2008) Knowing what works in health care: a roadmap for the nation. National Academies Pres, Washington

    Google Scholar 

  2. National Guideline Clearinghouse Web site, available at http://www.guideline.gov/index.aspx Updated October 18, 2010. Accessed 23 Oct 2010

  3. Stulberg JJ, Delaney CP, Neuhauser DV, Aron DC, Fu P, Koroukian SM (2010) Adherence to surgical care improvement project measures and the association with postoperative infections. JAMA 303(24):2479–2485. doi:10.1001/jama.2010.841

    Article  PubMed  CAS  Google Scholar 

  4. Berenguer CM, Ochsner MG, Lord SA, Senkowski CK (2010) Improving surgical site infections: using national surgical quality improvement program data to institute surgical care improvement project protocols in improving surgical outcomes. J Am Coll Surg 210(5):737–741

    Article  PubMed  Google Scholar 

  5. Martínez R, Reyes S, Lorenzo J, Menéndez R (2009) Impact of guidelines on outcome: the evidence. Semin Respir Crit Care Med 30(2):172, 178. doi:10.1055/s-0029-1202936

    Article  Google Scholar 

  6. Lesho EP, Myers CP, Ott M, Winslow C, Brown JE (2005) Do clinical practice guidelines improve processes or outcomes in primary care? Mil Med 170(3):243–246

    PubMed  Google Scholar 

  7. Weinberger M (2009) Seventeen years of asthma guidelines: why hasn’t the outcome improved for children? J Pediatr 154(6):786–788

    Article  PubMed  Google Scholar 

  8. Ellen M, Brown A, Cockerill R (2009) Do clinical practice guidelines influence length of stay in Ontario acute care hospitals? Healthc Q 12(4):64–71

    PubMed  Google Scholar 

  9. Faraday M, Hubbard H, Kosiak B, Dmochowski R (2009) Staying at the cutting edge: a review and analysis of evidence reporting and grading; the recommendations of the American Urological Association. BJU Int 104(3):294–297. doi:10.1111/j.1464-410X.2009.08729.x

    Article  PubMed  Google Scholar 

  10. Woolf SH (1992) Practice guidelines, a new reality in medicine. II. Methods of developing guidelines. Arch Intern Med 152:946–952

    Article  PubMed  CAS  Google Scholar 

  11. Weber KL (2009) The AAOS clinical practice guidelines. J Am Acad Orthop Surg 17(6):335–336

    PubMed  Google Scholar 

  12. Buie WD (2010) Clinical practice guidelines: appraising the evidence. Dis Colon Rectum 53(8):1107–1109

    Article  PubMed  Google Scholar 

  13. Qaseem A, Snow V, Owens DK, Shekelle P, The Clinical Guidelines Committee of the American College of Physicians (2010) The development of clinical practice guidelines and guidance statements of the American College of Physicians: summary of methods. Ann Intern Med 153(3):194–199. doi:10.1059/0003-4819-153-3-201008030-00010

    PubMed  Google Scholar 

  14. Mechanick JI, Camacho PM, Cobin RH, Garber AJ, Garber JR, Gharib H, Petak SM, Rodbard HW, Trence DL (2010) American Association of Clinical Endocrinologists. American Association of Clinical Endocrinologists protocol for standardized production of clinical practice guidelines–2010 update. Endocr Pract 16(2):270–283

    PubMed  Google Scholar 

  15. Pavlidis N, Hansen H, Stahel R (2010) ESMO clinical practice guidelines: development, implementation and dissemination. Ann Oncol 21(Suppl 5):v7–v8. doi:10.1093/annonc/mdq158

    Article  PubMed  Google Scholar 

  16. Sniderman AD, Furberg CD (2009) Why guideline-making requires reform. JAMA 301(4):429–431

    Article  PubMed  CAS  Google Scholar 

  17. Sinuff T, Patel RV, Adhikari NKJ, Meade MO, Schünemann HJ, Cook DJ (2008) Quality of professional society guidelines and consensus conference statements in critical care. Crit Care Med 36:1049–1058

    Article  PubMed  Google Scholar 

  18. Hurdowar A, Graham ID, Bayley M, Harrison M, Wood-Dauphinee S, Bhogal S (2007) Quality of stroke rehabilitation clinical practice guidelines. J Eval Clin Pract 13(4):657–664. doi:10.1111/j.1365-2753.2007.00708.x

    Article  PubMed  Google Scholar 

  19. Lopez-Olivo MA, Kallen MA, Ortiz Z, Skidmore B, Suarez-Almazor ME (2008) Quality appraisal of clinical practice guidelines and consensus statements on the use of biologic agents in rheumatoid arthritis: a systematic review. Arthritis Care Res 59(11):1625–1638. doi:10.1002/art.24207

    Article  Google Scholar 

  20. Dahm P, Yeung LL, Chang SS, Cookson MS (2008) A critical review of clinical practice guidelines for the management of clinically localized prostate cancer. J Urol 180(2):451–460

    Article  PubMed  Google Scholar 

  21. Tricoci P, Allen JM, Kramer JM, Califf RM, Smith SC Jr (2009) Scientific evidence underlying the ACC/AHA clinical practice guidelines. JAMA 301(8):831–841. doi:10.1001/jama.2009.205

    Article  PubMed  CAS  Google Scholar 

  22. Shaneyfelt TM, Centor RM (2009) Reassessment of clinical practice guidelines: go gently into that good night. JAMA 301(8):868–869. doi:10.1001/jama.2009.225

    Article  PubMed  CAS  Google Scholar 

  23. Cosgrove L, Bursztajn HJ, Krimsky S, Anaya M, Walker J (2009) Conflicts of interest and disclosure in the American Psychiatric Association’s clinical practice guidelines. Psychother Psychosom 78(4):228–232

    Article  PubMed  Google Scholar 

  24. Council of Medical Specialty Societies (CMSS) (2010) “Code for Interactions with Companies” available at http://www.cmss.org/codeforinteractions.aspx, accessed 23 Oct 2010

  25. European Association of Urology and American Urological Association (2007) Guideline for the Management of Ureteral Calculi. Available at http://www.auanet.org/content/guidelines-and-quality-care/clinical-guidelines.cfm?sub=uc, accessed 24 Oct 2010

  26. Hirsh J, Guyatt G (2009) Clinical experts or methodologists to write clinical guidelines? Lancet 374:273–275

    Article  PubMed  Google Scholar 

  27. Freeman MD (2010) Clinical practice guidelines versus systematic reviews; which serve as the best basis for evidence-based spine medicine? Spine J 10:512–513

    Article  PubMed  Google Scholar 

  28. Dahm P, Yeung LL, Gallucci M, Simone G, Schünemann HJ (2009) How to use a clinical practice guideline. J Urol 181(2):472–479

    Article  PubMed  Google Scholar 

  29. Torrijos RM, Glantz SA (2006) The US Public Heath Service “treating tobacco use and dependence clinical practice guidelines” as a legal standard of care. Tob Control 15:447–451

    Article  PubMed  Google Scholar 

  30. Moses RE, Feld AD (2008) Legal risks of clinical practice guidelines. Am J Gastroenterol 103:7–11

    PubMed  Google Scholar 

  31. Recupero PR (2008) Clinical practice guidelines as learned treatises: understanding their use as evidence in the courtroom. J Am Acad Psychiatry Law 36(3):290–301

    PubMed  Google Scholar 

  32. Matchar DB, Mark DB (2008) Strategies for incorporating resource allocation and economic considerations. Chest 133(Suppl 6):132S–140S. doi:10.1378/chest.08-0671

    Article  PubMed  Google Scholar 

  33. Guyatt G, Baumann M, Pauker S, Halperin J, Maurer J, Owens DK, Tosteson ANA, Carlin B, Gutterman D, Prins M, Lewis SZ, Schünemann H (2006) Addressing resource allocation issues in recommendations from clinical practice guideline panels. Chest 129(1):182–187. doi:10.1378/chest.129.1.182

    Article  PubMed  Google Scholar 

  34. Carlsen B, Glenton C, Pope C (2007) Thou shalt versus thou shalt not: a meta-synthesis of GPs’ attitudes to clinical practice guidelines. Br J Gen Pract 57:971–978

    Article  PubMed  Google Scholar 

  35. Nuckols T, Lim Y-W, Wynn B, Mattke S, MacLean C, Harber P, Brook R, Wallace P, Garland R, Asch S (2008) Rigorous development does not ensure that guidelines are acceptable to a panel of knowledgeable providers. J Gen Intern Med 23(1):37–44. doi:10.1007/s11606-007-0440-9

    Article  PubMed  Google Scholar 

  36. Lamy J-B, Ebrahiminia V, Riou C, Seroussi B, Bouaud J, Simon C, Dubois S, Butti A, Simon G, Favre M, Falcoff H, Venot A (2010) How to translate therapeutic recommendations in clinical practice guidelines into rules for critiquing physician prescriptions? Methods and application to five guidelines. BMC Med Inform Decis Mak 10(1):31

    Article  PubMed  Google Scholar 

  37. Connor SJ, Lienert AR, Brown LA, Bagshaw PF (2008) Closing the audit loop is necessary to achieve compliance with evidence-based guidelines in the management of acute pancreatitis. N Z Med J 121:19–25

    PubMed  Google Scholar 

  38. Harrison MB, Legare F, Graham ID, Fervers B (2010) Adapting clinical practice guidelines to local context and assessing barriers to their use. CMAJ 182(2):E78–E84. doi:10.1503/cmaj.081232

    PubMed  Google Scholar 

  39. Gaddis GM, Greenwald P, Huckson S (2007) Toward improved implementation of evidence-based clinical algorithms: clinical practice guidelines, clinical decision rules, and clinical pathways. Acad Emerg Med 14(11):1015–1022. doi:10.1111/j.1553-2712.2007.tb02382.x

    PubMed  Google Scholar 

  40. Kerfoot BP, Kearney MC, Connelly D, Ritchey ML (2009) Interactive spaced education to assess and improve knowledge of clinical practice guidelines: a randomized controlled trial. Ann Surg 249(5):744–749

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

None of the authors have any conflicts of interest in relation to this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. Stuart Wolf Jr.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wolf, J.S., Hubbard, H., Faraday, M.M. et al. Clinical practice guidelines to inform evidence-based clinical practice. World J Urol 29, 303–309 (2011). https://doi.org/10.1007/s00345-011-0656-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00345-011-0656-5

Keywords

Navigation