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Prevalence and clinical features of arthralgia/arthritis in healthy pregnant women

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Abstract

The authors prospectively investigated 155 pregnant women, without a history of rheumatic disease who visited the Department of Obstetrics and Gynecology for routine antenatal care, to evaluate the prevalences and clinical features of arthralgia and arthritis in healthy pregnant women. Mean of the 155 subjects’ ages was 31.8 ± 3.8 (years, ±SD). Arthralgia was found in 26 (16.7%) and arthritis in 15 (9.6%) pregnant women. Arthralgia or arthritis developed in the third trimester (28–40 weeks of gestation), except in one case (16 weeks of gestation). Most commonly involved joints were the proximal interphalangeal (n = 19, 12.2%). Rheumatoid factor and antinuclear antibody were negative in patients with arthritis. Ten women (6.8%) had persistent arthralgia for over 6 weeks, post-delivery. Four of them were followed up at Rheumatology Clinic and were diagnosed as having spondyloarthropathy (1), or unspecified arthralgia (3). In conclusion, arthralgia is common during pregnancy and most frequent in proximal interphalangeal joints.

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References

  1. Ritchie JR (2003) Orthopedic considerations during pregnancy. Clin Obstet Gynecol 46(2):456–466

    Article  PubMed  Google Scholar 

  2. Borg-Stein J, Dugan SA, Gruber J (2005) Musculoskeletal aspects of pregnancy. Am J Phys Med Rehabil 84(3):180–192

    Article  PubMed  Google Scholar 

  3. Lowery CL (1995) Sudden joint and extremity pain in pregnancy. Obstet Gynecol Clin North Am 22(1):173–190

    PubMed  CAS  Google Scholar 

  4. Albert H, Godskesen M, Westergaard J (2001) Prognosis in four syndromes of pregnancy-related pelvic pain. Acta Obstet Gynecol Scand 80(6):505–510

    Article  PubMed  CAS  Google Scholar 

  5. Albert H, Godskesen M, Westergaard J (2000) Evaluation of clinical tests used in classification procedures in pregnancy-related pelvic joint pain. Eur Spine J 9(2):161–166

    Article  PubMed  CAS  Google Scholar 

  6. Petri M (1997) Hopkins lupus pregnancy center: 1987 to 1996. Rheum Dis Clin North Am 23:1–14

    Article  PubMed  CAS  Google Scholar 

  7. Silman AJ, Kay A, Brennan P (1992) Timing of pregnancy in relation to the onset of rheumatoid arthritis. Arthritis Rheum 35:152–155

    Article  PubMed  CAS  Google Scholar 

  8. Barrett JH, Brennan P, Fiddler M, Silman AJ (1999) Does rheumatoid arthritis remit during pregnancy and relapse postpartum? Results from a nationwide study in the United Kingdom performed prospectively from late pregnancy. Arthritis Rheum 42(6):1219–1227

    Article  PubMed  CAS  Google Scholar 

  9. Iijima T, Tada H, Hidaka Y, Yagoro A, Mitsuda N, Kanzaki T, Murata Y, Amino N (1998) Prediction of postpartum onset of rheumatoid arthritis. Ann Rheum Dis 57(8):460–463

    Article  PubMed  CAS  Google Scholar 

  10. Ekman-Ordeberg G, Salgeback S, Ordeberg G (1987) Carpal tunnel syndrome in pregnancy. A prospective study. Acta Obstet Gynecol Scand 66(3):233–235

    Article  PubMed  CAS  Google Scholar 

  11. Schauberger CW, Rooney BL, Goldsmith L, Shenton D, Silva PD, Schaper A (1996) Peripheral joint laxity increases in pregnancy but does not correlate with serum relaxin levels. Am J Obstet Gynecol 174:667–671

    Article  PubMed  CAS  Google Scholar 

  12. Ostensen M, Forger F, Nelson JL, Schuhmacher A, Hebisch G, Villiger PM (2005) Pregnancy in patients with rheumatic disease: anti-inflammatory cytokines increase in pregnancy and decrease post partum. Ann Rheum Dis 64:839–844

    Article  PubMed  CAS  Google Scholar 

  13. Ruddy S, Harris ED, Sledge CB (eds) (2001) Kelley’s textbook of rheumatology. W·B Saunders Company, Philadelphia

    Google Scholar 

  14. Chi ZC, Ma SZ (2003) Rheumatologic manifestations of hepatic diseases. Hepatobiliary Pancreat Dis Int 2:32–37

    PubMed  Google Scholar 

  15. Schumann K (2001) Safety aspects of iron in food. Ann Nutr Metab 45:91–101

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Jong Kwan Jun or Yeong Wook Song.

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Choi, H.J., Lee, J.C., Lee, Y.J. et al. Prevalence and clinical features of arthralgia/arthritis in healthy pregnant women. Rheumatol Int 28, 1111–1115 (2008). https://doi.org/10.1007/s00296-008-0596-6

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  • DOI: https://doi.org/10.1007/s00296-008-0596-6

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