Abstract
Objective
The aim of this study was to investigate the adequacy of the following criteria for the classification of juvenile-onset spondyloarthropathies (JSpA): European Spondyloarthropathy Study Group criteria (ESSGCr) and Amor criteria (ACr) (proposed for adult SpA), Garmisch-Partenkirchen (G-PCr), seronegative enthesopathy and arthropathy syndrome (SEACr), and atypical spondyloarthropathies classification criteria (ASpCr) (proposed for JSpA).
Methods
Sixty-two patients with JSpA (48 male and 14 female) and 64 with juvenile idiopathic arthritis (27 male and 37 female) (excluding enthesitis-related and psoriatic arthritis) were enrolled in the study group. Twenty-nine of the patients with JSpA were diagnosed with definite JSpA and the remaining 35 with undifferentiated JSpA. One hundred six patients in the study group were evaluated by one investigator, who was unaware of the diagnosis, according to the following: ESSGCr, ACr, G-PCr, ASpCr, and SEACr.
Results
Analysis of the patients diagnosed with JSpA showed 83.9%, 82.3%, 95.2%, 61.3%, and 62.9% sensitivity and 87.5%, 95.3%, 78.1%, 98.4%, and 92.2% specificity for the ESSGCr, ACr, G-PCr, ASpCr, and SEACr sets, respectively.
Conclusion
None of the criteria evaluated above is sufficient for the classification of JSpA. There is a definite need for a new set of criteria with high specificity and sensitivity for early recognition and classification.
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References
Cassidy JT, Petty RE (2001) Juvenile ankylosing spondylitis. In: Petty RE, Cassidy JT (eds) Textbook of pediatric rheumatology. Saunders, Philadelphia, pp 323–344
Cabral D, Malleson P, Petty RE (1995) Spondyloarthropathies of childhood. Pediatr Clin North Am 42:1051–1070
Burgos-Vargas R (2002) The juvenile-onset spondyloarthropathies. Rheum Dis Clin North Am 28: 531–560
Prieur AM (1998) Spondyloarthropathies in childhood. Baillieres Clin Rheumatol 12:287–307
Southwood TR, Passo MH (1998) Spondyloarthropathies in childhood. In: Maddison PJ, Isenberg DA, Woo P, Glass DN (eds) Oxford textbook of rheumatology, vol 2. Oxford University Press, Oxford, pp 1049–1058
Bukulmez H, Colbert RA (2002) Juvenile spondyloarthropathies and related arthritis. Curr Opin Rheumatol 14:531–535
Schumacher HR, Bardin T (1998) The spondyloarthropathies: classification and diagnosis. Do we need new terminologies? Baillieres Clin Rheumatol 12:551–565
Burgos-Vargas R, Vazquez-Mellado J (1995) The early clinical recognition of juvenile onset ankylosing spondylitis and its differentiation from juvenile rheumatoid arthritis. Arthritis Rheum 38:835–844
Dougados M, Hochberg MC (2002) Why is the concept of spondyloarthropathies important? Best Pract Res Clin Rheumatol 16:495–505
Cabral DA, Oen KG, Petty RE (1992) SEA syndrome revisited: a long term follow up of children with a syndrome of seronegative enthesopathy and arthropathy. J Rheumatol 19:1282–1285
Burgos-Vargas R, Vazquez Mellado J, Cassis N et al (1996) Genuine ankylosing spondylitis in children: a case control study of patients with early definite disease according to adult onset criteria. J Rheumatol 23:2140–2147
Rosenberg AM, Petty RE (1982) A syndrome of seronegative enthesopathy and arthropathy in children. Arthritis Rheum 25:1041–1047
Hafner R (1987) Die juvenile Spondyloarthritis. Retrospektive Untersuchung an 71 Patienten. Monatsschr Kinderheilkd 135:41–46
Hussein A, Abdul Khaliq H, Von der Hardt H (1989) Atypical spondyloarthritis in children: proposed classification criteria. Eur J Pediatr 148:513–517
Amor B, Dougados M, Mijiyawa M (1990) Criteres de classification des spondylarthropathies. Rev Rheum Mal Osteoartic 57:85–89
Dougados M, van der Linden S, Juhlin R et al (1991) The European spondylarthropathy study group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 34:1218–1227
Prieur A-M, Dougados M, Listrat V, Amor B (1992) Evaluation of four sets of criteria for spondyloarthropathy in children: a multicentre European cross sectional study. Arthritis Rheum 35 [Suppl]:S190
Prieur A-M, Listrat V, Dougados M, Amor B (1993) Criteres de classification des spondylarthropathies chez les enfants. Arch Fr Pediatr 50:379–385
Van der Linden S, Valkenburg HA, Cats A (1984) Evaluation of classification criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum 27:361–368
Southwood TR, Petty RE, Malleson PN et al (1989) Psoriatic arthritis in children. Arthritis Rheum 32:1007–1013
Zeidler H, Man W, Khan MA (1992) Undifferentiated spondyloarthropathies. Rheum Clin North Am 18:187–202
Petty RE, Southwood T, Baum J et al (1998) Revision of the proposal classification criteria for juvenile idiopathic arthritis, 1997. J Rheumatol 25:1991–1994
Kasapçopur Ö, Çalışkan S, Yoloğlu N, Ercan G, Sever L, Özdoğan H, Arısoy N (2001) Evaluation of ILAR classification criteria for juvenile idiopathic arthritis in Turkish children. Ann Rheum Dis 60 [Suppl 11]:ii22 (P032)
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The authors gratefully acknowledge Yusuf Uygun for his technical assistance.
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Kasapçopur, Ö., Demirli, N., Özdoğan, H. et al. Evaluation of classification criteria for juvenile-onset spondyloarthropathies. Rheumatol Int 25, 414–418 (2005). https://doi.org/10.1007/s00296-004-0460-2
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DOI: https://doi.org/10.1007/s00296-004-0460-2