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Quorum-Sensing Mechanisms and Bacterial Response to Antibiotics in P. aeruginosa

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Abstract

Emergence and worldwide spreading of resistant bacteria to antibiotic have raised the importance for finding therapeutic alternative to compensate antibiotic drawbacks. Quorum sensing (QS) is a cell-to-cell communication involved in the development of various common bacterial behaviors including virulence factors expression, and targeting QS seems to be relevant to the struggle against bacterial infection. In this report, relevant literature on intrication of QS system and antimicrobial sensitivity mechanisms in P. aeruginosa PAO1 are reviewed.

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Acknowledgments

This research was supported by the Project PIC-Madagascar 2009 and the postdoctoral fellowship programs “ELAN 2015” and “ELAN 2016” of the ARES-CCD (Académie de Recherche et d’Enseignement Supérieur-Commission Coopération au Développement, Belgium).

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Authors and Affiliations

  1. Laboratoire de Biotechnologie-Microbiologie, Université d’Antananarivo, B.P 906, 101, Antananarivo, Madagascar

    Tsiry Rasamiravaka

  2. Laboratoire de Biotechnologie Végétale, Université Libre de Bruxelles, 12 rue des Professeurs Jenner et Brachet, 6041, Gosselies, Belgium

    Tsiry Rasamiravaka & Mondher El Jaziri

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  1. Tsiry Rasamiravaka
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Correspondence to Tsiry Rasamiravaka.

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Rasamiravaka, T., El Jaziri, M. Quorum-Sensing Mechanisms and Bacterial Response to Antibiotics in P. aeruginosa . Curr Microbiol 73, 747–753 (2016). https://doi.org/10.1007/s00284-016-1101-1

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