Skip to main content
SpringerLink
Log in

Treatment with valproic acid for myelofibrosis with myeloid metaplasia

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Tefferi A (2000 )Mylofibrosis with myeloid metaplasia. N Engl J Med 342:1255–1265

    Article  PubMed  CAS  Google Scholar 

  2. Kuendgen A, Strupp C, Aivado M, Bernhardt A, Hildebrandt B, Haas R, Germing U, Gattermann N (2004) Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid. Blood 104:1266–1269

    Article  PubMed  CAS  Google Scholar 

  3. Marks PA, Richon VM, Rifkind RA (2000) Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst 92:1210–1216

    Article  PubMed  CAS  Google Scholar 

  4. Gottlicher M, Minucci S, Zhu P, Kramer OH, Schimpf A, Giavara S, Sleeman JP, Coco FL, Nervi C, Pelicci PG, Heinzel T (2001) Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J 20:6969–6978

    Article  PubMed  CAS  Google Scholar 

  5. Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS (2001) Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 276:36734–36741

    Article  PubMed  CAS  Google Scholar 

  6. Mesa RA, Steensma DP, Pardanani A, Li CY, Elliott M, Kaufmann SH, Wiseman G, Gray LA, Schroeder G, Reeder T, Zeldis JB, Tefferi A (2003) A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia. Blood 101:2534–2541

    Article  PubMed  CAS  Google Scholar 

  7. Devine SM, Hoffman R, Verma A, Shah R, Bradlow BA, Stock W, Maynard V, Jessop E, Peace D, Huml M, Thomason D, Chen YH, Besien KV (2002) Allogenic blood cell transplantation following reduced-intensity conditioning is effective therapy for older patients with myelofibrosis with myeloid metaplasia. Blood 99:2255–2258

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Hematology and Oncology, Department of Internal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, 216-8511, Japan

    Yasuyuki Inoue, Takao Suzuki, Madoka Takimoto, Michiko Irei, Shinji Yoshioka, Yasushi Shibuya, Masayuki Kato, Mitsuru Koike & Masatomo Takahashi

Authors
  1. Yasuyuki Inoue
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Takao Suzuki
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Madoka Takimoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Michiko Irei
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shinji Yoshioka
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Yasushi Shibuya
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Masayuki Kato
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Mitsuru Koike
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Masatomo Takahashi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yasuyuki Inoue.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Inoue, Y., Suzuki, T., Takimoto, M. et al. Treatment with valproic acid for myelofibrosis with myeloid metaplasia. Ann Hematol 84, 833–834 (2005). https://doi.org/10.1007/s00277-005-1104-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-005-1104-7

Keywords

Search

Navigation