Skip to main content
Log in

Initial and Long-Term Results of Endovascular Therapy for Chronic Total Occlusion of the Subclavian Artery

  • Clinical Investigation
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Purpose

To study the initial and long-term results of angioplasty and primary stenting for the treatment of chronic total occlusion (CTO) of the subclavian artery (SA).

Materials and Methods

From January 1999 to February 2010, 56 patients (25 men with a mean age of 58 ± 8 years) underwent endovascular treatment for CTO of the SA. Duplex scans and arteriograms confirmed occlusion in all cases. Indications for recanalization were subclavian steal syndrome in 33 patients (58.1%), arm claudication in 13 patients (23.2%), and coronary ischemia in 7 patients (12.5%) who had a history of previous coronary artery bypass grafting that included left internal thoracic artery graft. Three patients (5.4%) were treated before the scheduled coronary artery bypass surgery, which included left internal thoracic artery graft. After successful recanalization, all arteries were stented, and all of the patients were followed-up at 1, 3, 6, and 12 months after surgery and annually thereafter.

Results

Successful recanalization of the SA was achieved in 46 patients (82.1%), and the complication rate was 7.1%. During follow-up (mean 40 ± 26 months; range 2 to 125), the primary patency rates after 1 and 3 years were 97.9% and 82.7%, respectively. At the end of follow-up, 76% of the arteries showed no evidence of restenosis. Univariate analysis failed to identify any variable predictive of long-term patency of successfully recanalized SA.

Conclusion

Percutaneous transluminal angioplasty with stenting of the complete total occlusion of the SA is a safe and effective procedure associated with low risks and good long-term results.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Fields WS, Lemak NA (1972) Joint study of extracranial arterial occlusion. Subclavian steal: a review of 168 cases. JAMA 222:1139–1143

    Article  PubMed  CAS  Google Scholar 

  2. Bates MC, Broce M, Lavigne PS, Stone P (2004) Subclavian artery stenting: factors influencing long-term outcome. Catheter Cardiovasc Interv 61:5–11

    Article  PubMed  Google Scholar 

  3. Motarjeme A, Keifer JW, Zuska AJ, Nabawi P (1985) Percutaneous transluminal angioplasty for treatment for subclavian steal. Radiology 155:611–613

    PubMed  CAS  Google Scholar 

  4. Sullivan TM, Gray BH, Bacharach JM, Perl J 2nd, Childs MB, Modzelewski L et al (1998) Angioplasty and primary stenting of the subclavian, innominate, and common carotid arteries in 83 patients. J Vasc Surg 28:1059–1065

    Article  PubMed  CAS  Google Scholar 

  5. Henry M, Amor M, Henry I, Ethevenot G, Tzvetanov K, Chati Z (1999) Percutaneous transluminal angioplasty of the subclavian arteries. J Endovasc Surg 6:33–41

    Article  PubMed  CAS  Google Scholar 

  6. Westerband A, Rodriguez JA, Ramaiah VG, Diethrich EB (2003) Endovascular therapy in prevention and management of coronary-subclavian steal. J Vasc Surg 38:699–703

    Article  PubMed  Google Scholar 

  7. Martinez R, Rodriguez-Lopez J, Torruella L, Ray L, Lopez-Galarza L, Diethrich EB (1997) Stenting for occlusion of the subclavian arteries. Tex Heart Inst J 24:23–27

    PubMed  CAS  Google Scholar 

  8. Al-Mubarak N, Liu MW, Dean LS, Al-Shaibi K, Chastain HD 2nd, Lyer SS et al (1999) Immediate and late outcomes of subclavian artery stenting. Catheter Cardiovasc Interv 46:169–172

    Article  PubMed  CAS  Google Scholar 

  9. Rodriguez-Lopez JA, Werner A, Martinez R, Torruella LJ, Ray LI, Diethrich EB (1999) Stenting for atherosclerotic occlusive disease of the subclavian artery. Ann Vasc Surg 13:254–260

    Article  PubMed  CAS  Google Scholar 

  10. Pollard H, Rigby S, Moritz G, Lau C (1998) Subclavian steal syndrome. A review. Australas Chiropr Osteopathy 7:20–28

    PubMed  Google Scholar 

  11. Hadjipetrou P, Cox S, Piemonte T, Eisenhauer A (1999) Percutaneous revascularization of atherosclerotic obstruction of aortic arch vessels. J Am Coll Cardiol 33:1238–1245

    Article  PubMed  CAS  Google Scholar 

  12. Mathias K, Jaeger H (1999) Proximal subclavian artery obstruction. In: Henry M, Amor M (eds) Tenth international course book of peripheral vascular intervention (ETC). Europa Organisation, Toulouse, France, pp 607–616

    Google Scholar 

  13. Eisenhauer AC, Shaw JA (2004) Atherosclerotic subclavian artery disease and revascularization. In: Abele GS (ed) Peripheral vascular disease, diagnostic and therapeutic approach. Lippioncott Williams & Wilkins, Philadelphia, pp 283–294

    Google Scholar 

  14. Mathias K, Schlosser V, Reinke M (1980) Katheterrekanalisation eines Subklaviaverschlusses. Roentgen Foretrific 132:346–347

    Article  CAS  Google Scholar 

  15. Bachman DM, Kim RM (1980) Transluminal dilatation for subclavian steal syndrome. Am J Roentgenol 135:995–996

    CAS  Google Scholar 

  16. Huttl K, Nemes B, Simonffy A, Entz L, Berczi V (2002) Angioplasty of the innominate artery in 89 patients: experience over 19 years. Cardiovasc Intervent Radiol 25:109–114

    Article  PubMed  Google Scholar 

  17. Smith JM, Koury HI, Hafner CD, Welling RE (1994) Subclavian steal syndrome. A review of 59 consecutive cases. J Cardiovasc Surg (Torino) 35:11–14

    CAS  Google Scholar 

  18. De Vries JP, Jager LC, Van den Berg JC, Overtoom TT, Ackerstaff RG, Van de Pavoordt ED et al (2005) Durability of percutaneous transluminal angioplasty for obstructive lesions of proximal subclavian artery: long term results. J Vasc Surg 41(1):19–23

    Article  PubMed  Google Scholar 

  19. Mathias KD, Luth I, Haarmann P (1993) Percutaneous transluminal angioplasty of proximal subclavian artery occlusions. Cardiovasc Intervent Radiol 16:214–218

    Article  PubMed  CAS  Google Scholar 

  20. Edwards WH, Mulherin JL Jr (1985) The surgical reconstruction of the proximal subclavian and vertebral artery. J Vasc Surg 2:634–642

    PubMed  CAS  Google Scholar 

  21. Wylie EJ, Effeney DJ (1979) Surgery of the aortic arch branches and vertebral arteries. Surg Clin North Am 59:669–680

    PubMed  CAS  Google Scholar 

  22. Motarjeme A (1996) Percutaneous transluminal angioplasty of supraaortic vessels. J Endovasc Surg 3:171–181

    Article  PubMed  CAS  Google Scholar 

  23. Motarjeme A, Gordon GI (1993) Percutaneous transluminal angioplasty of the brachiocephalic vessels: guidelines for therapy. Int Angiol 12:260–269

    PubMed  CAS  Google Scholar 

  24. Düber C, Klose KJ, Kopp H, Schmiedt W (1992) Percutaneous transluminal angioplasty for occlusion of the subclavian artery: short and long term results. Cardiovasc Intervent Radiol 15:205–210

    Article  PubMed  Google Scholar 

  25. Patel SN, White CJ, Collins TJ, Daniel GA, Jenkins JS, Reilly JP et al (2008) Catheter-based treatment of the subclavian and innominate arteries. Catheter Cardiovasc Interv 71(7):963–968

    Article  PubMed  Google Scholar 

  26. Przewlocki T, Kablak-Ziembicka A, Pieniazek P, Musialek P, Kadzielski A, Zalewski J et al (2006) Determinants of immediate and long-term results of subclavian and innominate artery angioplasty. Cathet Cardiovasc Interv 67:519–526

    Article  Google Scholar 

  27. Wang KQ, Wang ZG, Yang BZ, Yuan C, Zhang WD, Yuan B et al (2010) Long-term results of endovascular therapy for proximal subclavian arterial obstructive lesions. Chin Med J (Engl) 123(1):45–50

    Google Scholar 

  28. Hebrang A, Maskovic J, Tomac B (1991) Percutaneous transluminal angioplasty of the subclavian arteries: long term results in 52 patients. AJR Am J Roentgenol 156:1091–1094

    PubMed  CAS  Google Scholar 

  29. Kumar K, Dorros G, Bates MC, Palmer L, Mathiak L, Dufek C (1995) Primary stent deployment in occlusive subclavian artery disease. Cathet Cardiovasc Diagn 34:281–285

    Article  PubMed  CAS  Google Scholar 

  30. Sixt S, Rastan A, Schwarzwälder U, Bürgelin K, Noory E, Schwarz T et al (2009) Results after balloon angioplasty or stenting of atherosclerotic subclavian artery obstruction. Catheter Cardiovasc Interv 73(3):395–403

    Article  PubMed  Google Scholar 

  31. Qi L, Gu Y, Zhang J, Yu H, Li X, Guo L et al (2010) Surgical treatment of subclavian artery occlusion. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 24(9):1030–1032

    PubMed  Google Scholar 

  32. AbuRahma AF, Robinson PA, Tucker G (2000) Jennings carotid-subclavian bypass grafting with polytetrafluoroethylene grafts for symptomatic subclavian artery stenosis or occlusion: a 20-year experience. J Vasc Surg 32(3):411–419

    Article  PubMed  CAS  Google Scholar 

  33. Schardey HM, Meyer G, Rau HG, Gradl G, Jauch KW, Lauterjung L (1996) Subclavian carotid transposition: an analysis of a clinical series and a review of the literature. Eur J Vasc Endovasc Surg 12:431–436

    Article  PubMed  CAS  Google Scholar 

  34. Schillinger M, Haumer M, Schillinger S, Ahmadi R, Minar E (2001) Risk stratification for subclavian artery angioplasty: is there an increased rate of restenosis after stent implantation? J Endovasc Ther 8:550–557

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

This manuscript was partly founded by Grant No. 41002 given by Ministry of Science and Technological Development of Republic of Serbia.

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Srdjan Babic.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Babic, S., Sagic, D., Radak, D. et al. Initial and Long-Term Results of Endovascular Therapy for Chronic Total Occlusion of the Subclavian Artery. Cardiovasc Intervent Radiol 35, 255–262 (2012). https://doi.org/10.1007/s00270-011-0144-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00270-011-0144-8

Keywords

Navigation