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Sodium Tetradecyl Sulphate Direct Intralesional Sclerotherapy of Venous Malformations of the Vulva and Vagina: Report of Five Cases

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Abstract

We report five cases of female patients affected by symptomatic focal external genital venous malformations treated with percutaneous direct intralesional injection of sodium tetradecyl sulphate (STS). All patients were referred because of discomfort and pain when sexual intercourse was attempted. Direct sclerotherapy with 3% STS was performed on a day-hospital basis with the patient under local anesthesia. Complete resolution of the symptoms was achieved in all cases. No major adverse effects were reported. Direct intralesional sclerotherapy with STS may be considered a safe and effective method for the treatment of female external genital malformation without the necessity of general anesthesia for pain control.

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References

  1. Burrows PE, Mulliken JB, Fellows KE et al (1983) Childhood hemangiomas and vascular malformations angiographic differentiation. AJR Am J Roentgenol 141:483–488

    CAS  PubMed  Google Scholar 

  2. Eifert S, Villavicencio JL, Kao TC et al (2000) Prevalence of deep venous anomalies in congenital vascular malformations of venous predominance. J Vasc Surg 31:462–471

    Article  CAS  PubMed  Google Scholar 

  3. Marrocco-Trischitta MM, Nicodemi EM, Nater C et al (2001) Management of congenital venous malformations of the vulva. Obstet Gynecol 98:789–793

    Article  CAS  PubMed  Google Scholar 

  4. Yamaki T, Nozaki M, Sasaki K (2000) Color duplex-guided sclerotherapy for the treatment of venous malformations (VMs). Dermatol Surg 26:323–328

    Article  CAS  PubMed  Google Scholar 

  5. Vikkula M, Boon LM, Mulliken JB (2001) Molecular genetics of vascular malformations. Matrix Biol 20:327–335

    Article  CAS  PubMed  Google Scholar 

  6. Herman AR, Morello F, Strickland JL (2004) Vulvar venous malformations in an 11-year-old girl: a case report. J Pediatr Adolesc Gynecol 17:179–181

    Article  PubMed  Google Scholar 

  7. Shireman P, McCarthy W, Yao J et al (1997) Treatment of venous malformations by direct injection with ethanol. J Vasc Surg 26:838–844

    Article  CAS  PubMed  Google Scholar 

  8. Reiner L (1946) The activity of anionic surface active compounds in producing vascular obliteration. Proc Soc Exp Biol Med 62:49–54

    CAS  PubMed  Google Scholar 

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The authors declare that they have no conflict of interest.

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Correspondence to Miltiadis Krokidis.

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Krokidis, M., Venetucci, P., Hatzidakis, A. et al. Sodium Tetradecyl Sulphate Direct Intralesional Sclerotherapy of Venous Malformations of the Vulva and Vagina: Report of Five Cases. Cardiovasc Intervent Radiol 34 (Suppl 2), 228–231 (2011). https://doi.org/10.1007/s00270-010-9916-9

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  • DOI: https://doi.org/10.1007/s00270-010-9916-9

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