Abstract
Patients with breast or thyroid cancer with metastatic spinal tumours are expected to survive relatively longer than patients with other cancers with metastatic spinal tumours. The purpose of this study was to determine the clinical characteristics of long-term survivors of breast or thyroid cancer with metastatic spinal tumours. We studied the clinical profile of long-term survivors by comparing the characteristics of nine patients who had survived for at least 5 years after a spinal operation with the characteristics of 16 patients who had not. Our results showed that the longer the time from the diagnosis of the primary cancer to the spinal operation, the longer patients with breast or thyroid cancer and metastatic spinal tumours would survive. Six of the eight patients (75.0%) who had undergone the spinal operation at least 5 years after the diagnosis of the primary cancer survived especially long. In conclusion, the duration from the diagnosis of the primary cancer to the spinal operation is very useful for predicting a prognosis in patients with breast or thyroid cancer and metastatic spinal tumours.
Résumé
Les patients présentant des métastases rachidiennes de cancer du sein ou de la thyroide ont classiquement une survie plus longue qu’avec les autres cancer. Le but de cette étude est de déterminer les caractéristiques cliniques de ces longues survies. Nous avons comparé 9 patients qui avaient une survie d’au moins 5 ans après intervention rachidienne pour métastases avec 16 qui n’avaient pas cette longue survie. Les résultats montrent que plus le délai entre le diagnostic du cancer primitif du sein ou de la thyroide et l’intervention rachidienne est long plus la survie est longue. Six des huit patients (75%) qui avaient l’opération rachidienne au moins 5 ans après le diagnostic du cancer primitif avaient une survie particulièrement longue. En conclusion le délai entre le diagnostic du cancer primitif et l’opération du rachis est un bon élément prédictif du pronostic chez les patients atteint d’un cancer du sein ou de la thyroide avec des métastases rachidiennes.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Helweg-Larsen S (1996) Clinical ontcome in metastatic spinal cord compression. A prospective study of 153 patients. Acta Neurol Scand 94:269–275
Hirabayashi H, Ebara S, Kinoshita T et al (2003) Clinical outcome and survival after palliative surgery for spinal metastasis. Cancer 97:476–484
Kostuik JP, Errico TJ, Gleason TF et al (1988) Spinal stabilization of vertebral column tumors. Spine 13:250–256
Magerl F, Coscia MF (1988) Total posterior vertebrectomy of the thoracic or lumbar spine. Clin Orthop 232:62–69
Rades D, Heidenreich F, Karstens JH (2002) Final results of a prospective study of the prognostic value of the time to develop motor deficits before irradiation in metastatic spinal cord compression. Int J Radiation Oncology Biol Phys 53:975–979
Sundaresan N, Digiacinto GV, Hughes JE et al (1991) A treatment of neoplastic spinal cord compression: results of a prospective study. Neurosurgery 29:645–650
Tatsui H, Onomura T, Morishita S et al (1996) Survival rates of patients with metastatic spinal cancer after scintigraphic detection of abnormal radioactive accumulation. Spine 21:2143–2148
Tokuhashi Y, Matsuzaki H, Toriyama S et al (1990) Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. Spine 15:1110–1113
Tomita K, Kawahara N, Baba H et al (1997) Total en bloc spondylectomy: a new surgical technique for primary malignant vertebral tumors. Spine 22:324–333
Tomita K, Kawahara N, Kobayashi T et al (2001) Surgical strategy for spinal metastases. Spine 26:298–306
van der Linden YM, Dijkstra SPDS, Vonk EJA et al (2005) Prediction of survival in patients with metastases in the spinal column. Cancer 103:320–328
Zaidat OO, Ruff RL (2002) Treatment of spinal epidural metastasis improves patient survival and functional state. Neurology 58:1360–1366
Author information
Authors and Affiliations
Corresponding author
Additional information
An erratum to this article can be found at http://dx.doi.org/10.1007/s00264-006-0263-z
Rights and permissions
About this article
Cite this article
Kasai, Y., Kawakita, E. & Uchida, A. Clinical profile of long-term survivors of breast or thyroid cancer with metastatic spinal tumours. International Orthopaedics (SICOT) 31, 171–175 (2007). https://doi.org/10.1007/s00264-006-0145-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00264-006-0145-4