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Muscular sarcoidosis involving the chest and abdominal walls: case report with MR imaging

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Abstract

Sarcoidosis is an inflammatory disorder that is characterized by the presence of noncaseating granulomas in tissues, involving many organs and tissues. Extra-pulmonary, especially muscular sarcoidosis is a rare condition. The most common location of the muscular sarcoidosis is known to be the proximal muscles of the extremities; however, there have been no cases of diffuse involvement of the chest and abdominal wall muscles. Here, we report a rare muscular sarcoidosis with infiltrative pattern in the chest and abdominal wall muscles and describe the MR imaging findings that were mistaken as lymphoma at initial diagnosis. Although our case did not show characteristic MR findings of muscular sarcoidosis, clinicians or radiologists who are aware of these imaging features can perform early systemic survey for sarcoidosis. Also muscle biopsy is very important to confirm the sarcoidosis and distinguish it from other tumors.

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References

  1. Matsuo M, Ehara S, Tamakawa Y, Chida E, Nishida J, Sugai T. Muscular sarcoidosis. Skelet Radiol. 1995;24:535–7.

    Article  CAS  Google Scholar 

  2. Moore SL, Teirstein AE. Musculoskeletal sarcoidosis: spectrum of appearances at MR imaging. Radiographics. 2003;23:1389–99.

    Article  PubMed  Google Scholar 

  3. Vardhanabhuti V, Venkatanarasimha N, Bhatnagar G, et al. Extra-pulmonary manifestations of sarcoidosis. Clin Radiol. 2012;67:263–76.

    Article  CAS  PubMed  Google Scholar 

  4. Otake S, Imagumbai N, Suzuki M, Ohba S. MR imaging of muscular sarcoidosis after steroid therapy. Eur Radiol. 1998;8:1651–3.

    Article  CAS  PubMed  Google Scholar 

  5. Heckmann JG, Stefan H, Heuss D, Hopp P, Neundorfer B. Isolated muscle sarcoidosis. Eur J Neurol. 2001;8:365–6.

    Article  CAS  PubMed  Google Scholar 

  6. Fayad F, Lioté F, Berenbaum F, Orcel P, Bardin T. Muscle involvement in sarcoidosis: a retrospective and followup studies. J Rheumatol. 2006;33(1):98–103.

    PubMed  Google Scholar 

  7. Jamal MM, Cilursu AM, Hoffman EL. Sarcoidosis presenting as acute myositis: report and review of the literature. J Rheumatol. 1988;15(12):1868–71.

    CAS  PubMed  Google Scholar 

  8. Tohme-Noun C, Le Breton C, Sobotka A, Boumenir ZE, Mileron B, Carette MF, et al. Imaging findings in three cases of the nodular type of muscular sarcoidosis. AJR. 2004;183(4):995–9.

    Article  CAS  PubMed  Google Scholar 

  9. Kobayashi H, Kotoura Y, Sakahara H, Yamamuro T, Endo K, Konishi J. Solitary muscular sarcoidosis: CT, MRI, and scintigraphic characteristics. Skelet Radiol. 1994;23:293–5.

    Article  CAS  Google Scholar 

  10. Douglas AC, MacLeod JG, Matthews JD. Symptomatic sarcoidosis of skeletal muscle. J Neurol Neurosurg Psychiatry. 1973;36:1034–40.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Aptel S, Lecocq-Teixeira S, Olivier P, Regent D, Teixeira PG, Blum A. Multimodality evaluation of musculoskeletal sarcoidosis: imaging findings and literature review. Diagn Interv Imaging. 2016;97:5–18.

    Article  CAS  PubMed  Google Scholar 

  12. Moore SL, Teirstein A, Golimbu C. MRI of sarcoidosis patients with musculoskeletal symptoms. AJR. 2005;185:154–9.

    Article  PubMed  Google Scholar 

  13. Parrish S, Turner JF. Diagnosis of sarcoidosis. Dis Mon. 2009;55:693–703.

    Article  PubMed  Google Scholar 

  14. Licharew A. Moskauer venerologische und dermatologische Gesellschaft. Dermatol Zentralbl. 1908;11:253–4.

    Google Scholar 

  15. Levine CD, Miller JJ, Stanislaus G, Wachsberg RH, Simmons MZ. Sarcoid myopathy: imaging findings. J Clin Ultrasound. 1997;25(9):515–7.

    Article  CAS  PubMed  Google Scholar 

  16. Zisman D, Biermann JS, Martinez F, et al. Sarcoidosis presenting as a tumor-like muscular lesion: case report and review of the literature. Medicine. 1999;78:112–22.

    Article  CAS  PubMed  Google Scholar 

  17. Sohn HS, Kim EN, Park JM, Chung YA. Muscular sarcoidosis: Ga-67 scintigraphy and magnetic resonance imaging. Clin Nucl Med. 2001;26(1):29–32.

    Article  CAS  PubMed  Google Scholar 

  18. Otake S. Sarcoidosis involving skeletal muscle: imaging findings and relative value of imaging procedures. AJR. 1994;162:369–75.

    Article  CAS  PubMed  Google Scholar 

  19. Otake S, Ishigaki T. Muscular sarcoidosis. Semin Musculoskelet Radiol. 2001;5:167–70.

    Article  CAS  PubMed  Google Scholar 

  20. May DA, Disler DG, Jones EA, Balkissoon AA, Manaster BJ. Abnormal signal intensity in skeletal muscle at MR imaging: patterns, pearls, and pitfalls. Radiographics. 2000;20:S295–315.

    Article  PubMed  Google Scholar 

  21. Funk SD, Kremer JM. Cutaneous and musculoskeletal features, diagnostic modalities, and immunopathology in sarcoidosis. Curr Opin Rheumatol. 1994;6:78–81.

    Article  Google Scholar 

  22. Otake S, Banno T, Ohba S, Noda M, Yamamoto M. Muscular sarcoidosis : findings at MR imaging. Radiology. 1990;176:145–8.

    Article  CAS  PubMed  Google Scholar 

  23. Komatsuda M, Nagao T, Arimori S. An autopsy case of malignant lymphoma associated with remarkable infiltration in skeletal muscles. Rinsho Ketsueki. 1981;22:891–5.

    CAS  PubMed  Google Scholar 

  24. Malloy PC, Fishman EK, Magid D. Lymphoma of bone, muscle and skin: CT findings. AJR Am J Roentgenol. 1992;159:805–9.

    Article  CAS  PubMed  Google Scholar 

  25. Lim CY, Ong KO. Imaging of musculoskeletal lymphoma. Cancer Imaging. 2013;13:448–57.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Chun CW, Jee WH, Park HJ, et al. MRI features of skeletal muscle lymphoma. AJR Am J Roentgenol. 2010;195:1355–60.

    Article  PubMed  Google Scholar 

  27. Carroll G, Breidahl W, Robbins P. Musculoskeletal lymphoma: MRI of bone or soft tissue presentations. J Med Imaging Radiat Oncol. 2013;57(6):663–73.

    Article  PubMed  Google Scholar 

  28. Simmonds NJ, Hoffbrand BI. Contracturing granulomatous myositis: a separate entity. J Neurol Neurosurg Psychiatry. 1990;53:998.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Woodard BH, Rosenberg SI, Farnham R, Adams DO. Incidence and nature of primary granulomatous inflammation in surgically removed material. Am J Surg Pathol. 1982;6(2):119–29.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, Pusan National University Hospital, Biomedical Research Institute, 1-10 Ami-dong, Seo-gu, Busan, 602-739, South Korea

    Seunghyun Lee, In Sook Lee & You Seon Song

  2. Pusan National University School of Medicine, Busan, South Korea

    Seunghyun Lee, In Sook Lee & You Seon Song

  3. Department of Internal Medicine, Pusan National University Hospital, Biomedical Research Institute, 1-10 Ami-dong, Seo-gu, Busan, 602-739, South Korea

    Jeongha Mok

  4. Department of Pathology, Pusan National University Hospital, Biomedical Research Institute, 1-10 Ami-dong, Seo-gu, Busan, 602-739, South Korea

    Kyung-Un Choi

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  1. Seunghyun Lee
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  2. In Sook Lee
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Correspondence to In Sook Lee.

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Lee, S., Lee, I.S., Mok, J. et al. Muscular sarcoidosis involving the chest and abdominal walls: case report with MR imaging. Skeletal Radiol 47, 407–411 (2018). https://doi.org/10.1007/s00256-017-2787-2

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  • DOI: https://doi.org/10.1007/s00256-017-2787-2

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