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Low-dose fetal CT for evaluation of severe congenital skeletal anomalies: preliminary experience

  • Advances in Fetal and Neonatal Imaging
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Abstract

Congenital skeletal abnormalities compose a heterogeneous and complex group of conditions that affect bone growth and development and result in various anomalies in shape and size of the skeleton. Prenatal sonographic diagnosis of these anomalies is challenging because of the relative rarity of each skeletal dysplasia, the multitude of differential diagnoses encountered when the bony abnormalities are identified, lack of precise molecular diagnosis and the fact that many of these disorders have overlapping features and marked phenotypic variability. The following review is a preliminary summary of our experience at the Children’s Hospital of Philadelphia (CHOP) using low-dose fetal CT in the evaluation of severe fetal osseous abnormalities.

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Disclaimer

The supplement this article is part of is not sponsored by the industry. Dr. Victoria, Dr. Epelman, Dr. Bebbington, Dr. Johnson, Dr. Kramer, Dr. Wilson, and Dr. Jaramillo have no financial interest, investigational or off-label uses to disclose.

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Authors and Affiliations

  1. Diagnostic Imaging, Children’s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19103, USA

    Teresa Victoria, Monica Epelman, Ann M. Johnson, Sandra Kramer & Diego Jaramillo

  2. Center for Fetal Diagnosis and Treatment, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Michael Bebbington

  3. Obstetrics & Gynecology, University of Calgary, Calgary, Canada

    R. Douglas Wilson

Authors
  1. Teresa Victoria
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  2. Monica Epelman
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  3. Michael Bebbington
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  4. Ann M. Johnson
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  5. Sandra Kramer
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  6. R. Douglas Wilson
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  7. Diego Jaramillo
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Corresponding author

Correspondence to Teresa Victoria.

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Victoria, T., Epelman, M., Bebbington, M. et al. Low-dose fetal CT for evaluation of severe congenital skeletal anomalies: preliminary experience. Pediatr Radiol 42 (Suppl 1), 142–149 (2012). https://doi.org/10.1007/s00247-011-2175-3

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  • DOI: https://doi.org/10.1007/s00247-011-2175-3

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