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Optic nerve and chiasm enlargement in a case of infantile Krabbe disease: quantitative comparison with 26 age-matched controls

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Abstract

Hypertrophy of the optic nerves and optic chiasm is described in a 5-month-old boy with infantile Krabbe disease. Optic nerve and optic chiasm hypertrophy is a rarely described feature of Krabbe disease. The areas of the prechiasmatic optic nerves and optic chiasm were measured and compared with those of 26 age-matched controls. The areas of the prechiasmatic optic nerves and optic chiasm were 132% and 53% greater than normal, respectively.

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Authors and Affiliations

  1. Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA

    Bhairav Patel, Barjor Gimi & Korgun Koral

  2. Department of Developmental Disabilities, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA

    Behroze Vachha

  3. Department of Neurology, Children’s Medical Center Dallas, Dallas, TX, USA

    Satish Agadi

  4. Department of Radiology, Children’s Medical Center Dallas, 1935 Medical District Dr., Dallas, TX, 75235, USA

    Korgun Koral

Authors
  1. Bhairav Patel
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  2. Barjor Gimi
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  3. Behroze Vachha
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  4. Satish Agadi
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  5. Korgun Koral
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Corresponding author

Correspondence to Korgun Koral.

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Patel, B., Gimi, B., Vachha, B. et al. Optic nerve and chiasm enlargement in a case of infantile Krabbe disease: quantitative comparison with 26 age-matched controls. Pediatr Radiol 38, 697–699 (2008). https://doi.org/10.1007/s00247-008-0849-2

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  • DOI: https://doi.org/10.1007/s00247-008-0849-2

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