Abstract
Extraskeletal osteosarcoma (ESOS) is a rare malignant tumor composed of mesenchymal cells comprising approximately 1% of soft-tissue sarcomas and 4% of all osteosarcomas. Primary osseous osteosarcomas more commonly develop in children and adolescents, but there are very few reports of ESOS occurring in those younger than 40 years. These variants of high-grade osteosarcoma are often characterized histopathologically by the production of an osteoid matrix and bone from malignant osteoblasts that by definition are present in the soft tissue outside the normal skeletal anatomy. We present a 13-year-old girl with a gradually enlarging, painless left thigh mass.
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References
Van Rijswijk CS, Lieng JG, Kroon HM et al (2001) Retroperitoneal extraskeletal osteosarcoma. J Clin Pathol 54:77–78
Abeloff MD, Armitage JO, Niedehuber JE et al (eds) (2004) Clinical oncology, 3rd edn. Elsevier, Orlando, pp 2503–2504
Kransdorf MJ, Murphey MD (eds) (1997) Imaging of soft tissue tumors. Saunders, Philadelphia, pp 333–335
Lidang Jensen M, Schumacher B, Myhre-Jensen O et al (1998) Extraskeletal osteosarcomas: a clinicopathologic study of 25 cases. Am J Surg Pathol 22:588–594
Chung EB, Enzinger FM (1987) Extraskeletal osteosarcoma. Cancer 60:1132–1142
Okada K, Ito H, Miyakoshi N et al (2003) A low-grade extraskeletal osteosarcoma. Skeletal Radiol 32:165–169
Abramovici LC, Hytiroglou P, Klein RM et al (2005) Well-differentiated extraskeletal osteosarcoma: report of 2 cases, 1 with dedifferentiation. Hum Pathol 36:439–443
Wodowski K, Hill DA, Pappo AS et al (2003) A chemosensitive pediatric extraosseous osteosarcoma: a case report and review of the literature. J Pediatr Hematol Oncol 25:73–77
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Beall, D.P., Ly, J., Bell, J.P. et al. Pediatric extraskeletal osteosarcoma. Pediatr Radiol 38, 579–582 (2008). https://doi.org/10.1007/s00247-007-0739-z
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DOI: https://doi.org/10.1007/s00247-007-0739-z