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Near Infrared Spectroscopy Describes Physiologic Payback Associated With Excess Postexercise Oxygen Consumption in Healthy Controls and Children With Complex Congenital Heart Disease

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Abstract

Exercise creates a physiologic burden with recovery from such effort crucial to adaptation. Excess postexercise oxygen consumption (EPOC) refers to the body’s increased metabolic need after work. This investigation was designed to determine the role of near infrared spectroscopy (NIRS) in the description of exercise recovery in healthy controls (NL) and children with congenital heart disease (CHD). Subjects were recruited with exercise testing performed to exhaustion. Exercise time (EXT), heart rate (HR), and oxygen consumption (VO2) were measured. Four-site NIRS (brain, kidney, deltoid, and vastus lateralis) were measured during exercise and into recovery to establish trends. Fifty individuals were recruited for each group (NL = 26 boys and 24 girls; CHD = 33 boys and 17 girls). Significant differences existed between EXT, VO2, and peak HR (P < 0.01). NIRS values were examined at four distinct intervals: rest, peak work, and 2 and 5 min after exercise. Significant cerebral hyperemia was seen in children with CHD post exercise when compared to normal individuals in whom redistribution patterns were directed to somatic muscles. These identified trends support an immediate compensation of organ systems to re-establish homeostasis in peripheral beds through enhanced perfusion. Noninvasive NIRS monitoring helps delineate patterns of redistribution associated with EPOC in healthy adolescents and children with CHD.

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Acknowledgments

This research was funded by a Pilot Innovative Research Award, Children’s Research Institute, Children’s Health System, Milwaukee, WI, and The Mend-a-Heart Foundation, Clarendon Hills, IL.

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Authors and Affiliations

  1. Herma Heart Center, Children’s Hospital of Wisconsin, PO Box 1997, Milwaukee, WI, 53201-1997, USA

    Michael J. Danduran & Jennifer E. Dixon

  2. Divisions of Pediatrics and Cardiology and Critical Care, Medical College of Wisconsin, Milwaukee, WI, USA

    Rohit P. Rao

Authors
  1. Michael J. Danduran
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  2. Jennifer E. Dixon
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  3. Rohit P. Rao
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Correspondence to Michael J. Danduran.

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Danduran, M.J., Dixon, J.E. & Rao, R.P. Near Infrared Spectroscopy Describes Physiologic Payback Associated With Excess Postexercise Oxygen Consumption in Healthy Controls and Children With Complex Congenital Heart Disease. Pediatr Cardiol 33, 95–102 (2012). https://doi.org/10.1007/s00246-011-0097-3

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