Abstract
The aim of the study to compare outcomes of flexible ureterorenoscopy in patients with different body mass index (BMI) scores and to explore whether the BMI has an effect on outcomes of RIRS. Five hundred and two patients who underwent flexible URS in 3 centers between 2008 and 2012 for the management of single upper urinary tract calculi were retrospectively reviewed. Patients were categorized as normal weight BMI 18.5 to 24.99 kg/m2, overweight 25 to 29.99 kg/m2, obese 30 to 39.99 kg/m2 and morbid obese >40 kg/m2.The groups were assessed in terms of demographic parameters including age, gender, stone size, intraoperative and postoperative variables. The mean patient age was 41.3 ± 15.51 (18–81) years and with an average BMI 26.68 ± 5.2 kg/m2 (16.64–55.15 kg/m²). Of the patients, 43.2 % had normal weight (NW), 32.2 % were overweight (OW), 21.9 % were obese (O) and 2.5 % were morbidly obese (MO). Stone-free rates after single procedure in NW, OW, O, MO groups were 60.8, 61.7, 73.6, 61.5 %, respectively (p = 0.079). Overall targeted stone-free rates were also similar in four groups (88.9, 90.1, 93.6, 90.4 %, p = 0.586). There were no statistically significant differences in the frequency of complications and mean hospitalization time among the groups (p > 0.05). In conclusion, this study demonstrated that flexible URS is a valuable option for the treatment of kidney stone in both obese and non-obese patients. BMI did not influence the postoperative outcomes.
Similar content being viewed by others
References
Maalouf NM, Cameron MA, Moe OW et al (2004) Novel insights into the pathogenesis of uric acid nephrolithiasis. Curr Opin Nephrol Hypertens 13:181–189
Pearle MS (2004) Metabolic risk factors and the impact of medical therapy on the management of nephrolithiasis in obese patients. Int Braz J Urol 30:338–339
Siener R, Glatz S, Nicolay C et al (2004) The role of overweight and obesity in calcium oxalate stone formation. Obes Res 12:106–113
Calvert RC, Burgess NA (2005) Urolithiasis and obesity: metabolic and technica considerations. Curr Opin Urol 15:113–117
Duffey BG, Pedro RN, Kriedberg C et al (2008) Lithogenic risk factors in the morbidly obese population. J Urol 179:1401–1406
Pasulka PS, Bistrian BR, Benotti PN et al (1986) The risks of surgery in the obese. Ann Intern Med 104:540–546
Murota-Kawano A, Ohya K, Sekine H (2008) Outpatient basis extracorporeal shock wave lithotripsy for ureter stones: efficacy of the third generation lithotripter as the first line treatment. Int J Urol 15:210–215
Delakas D, Karyotis I, Daskalopoulos G et al (2003) Independent predictors of failure of shockwave lithotripsy for ureteral stones employing a second-generation lithotripter. J Endourol 17:201–205
Muñoz RD, Tirolien PP, Belhamou S et al (2003) Treatment of reno-ureteral lithiasis with ESWL in obese patients. Apropos of 150 patients. Arch Esp Urol 56:933–938
Türk C, Knoll T, Petrik A et al (2012) Guidelines on Urolithiasis. http://www.uroweb.org/gls/pdf/20_Urolithiasis.pdf. Accessed Feb 2012
Binbay M, Yuruk E, Akman T et al (2010) Is there a difference in outcomes between digital and fiberoptic flexible ureterorenoscopy procedures? J Endourol 24:1929–1934
Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213
(2011) WHO Global Infobase Data for Saving Lives http://apps.who.int/infobase/?id=1. Accessed 9 Aug 2011
Semins MJ, Shore AD, Makary MA et al (2010) The association of increasing body mass index and kidney stone disease. J Urol 183:571–575
Delorme G, Huu Y, Liliaz J et al (2012) Ureterorenoscopy with Holmium- Yttrium- Aluminum- Garnet fragmentation is a safe and efficient tecnique for stone treatment in patients with body mass index superior to 30 kg/m2. J Endourol 26:239–243
Thomas R, Cass AS (1993) Extracorporeal shock wave lithotripsy in morbidly obese patients. J Urol 150:30–32
Pareek G, Armenakas NA, Fracchia JA (2003) Hounsfield units on computerized tomography predict stone-free rates after extra corporeal shock wave lithotripsy. J Urol 169:1679–1681
Carson CC 3rd, Danneberger JE, Weinerth JL (1988) Percutaneous lithotripsy in morbid obesity. J Urol 139:243–245
Faerber GJ, Goh M (1997) Percutaneous nephrolithotripsy in the morbidly obese patient. Tech Urol 3:89–95
Pearle MS, Nakada SY, Womack JS, Kryger J (1998) Outcomes of contemporary percutaneous nephrostolithotomy in morbidly obese patients. J Urol 160:669–673
Fuller A, Razvi H, Denstedt JD, Nott L, Pearle M, Cauda F, Bolton D, Celia A, de la Rosette J (2012) CROES PCNL Study Group: the CROES Percutaneous Nephrolithotomy Global Study: The Influence of Body Mass Index on Outcome. J Urol 188:138–144
Karlsen SJ, Renkel J, Tahir AR et al (2007) Extracorporeal shockwave lithotripsy versus ureteroscopy for 5- to 10-mm stones in the proximal ureter: prospective effectiveness patient-preference trial. J Endourol 21:28–33
Dash A, Schuster TG, Hollenbeck BK et al (2002) Ureteroscopic treatment of renal calculi in morbidly obese patients: a stone matched comparison. Urology 60:393–397
Andreoni C, Afane J, Olweny E et al (2001) Flexible ureteroscopic lithotripsy: first line therapy for proximal ureteral and renal calculi in the morbidly obese and superobese patient. J Endourol 15:493–498
Bozkurt OF, Resorlu B, Yildiz Y, Can CE, Unsal A (2011) Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm. J Endourol 25:1131–1135
Chew BH, Zavaglia B, Paterson RF et al (2013) A multicenter comparison of the safety and effectiveness of ureteroscopic laser lithotripsy in obese and normal weight patients. J Endourol 27:710–714
Caskurlu T, Atis G, Arikan O et al (2013) The impact of body mass index on the outcomes of retrograde intrarenal stone surgery. Urology 81:517–521
Bultitude MF, Tiptaft RC, Dasgupta P, Glass JM (2004) Treatment of urolithiasis in the morbidly obese. Obes Surg 14:300–304
Akman T, Binbay M, Ugurlu M et al (2012) Outcomes of retrograde intrarenal surgery compared with percutaneous nephrolithotomy in elderly patients with moderate-size kidney stones: a matched-pair analysis. J Endourol 26:625–629
Conflict of interest
None of the authors have financial support.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Sari, E., Tepeler, A., Yuruk, E. et al. Effect of the body mass index on outcomes of flexible ureterorenoscopy. Urolithiasis 41, 499–504 (2013). https://doi.org/10.1007/s00240-013-0590-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00240-013-0590-7