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A review of biosensing techniques for detection of trace carcinogen contamination in food products

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Abstract

Carcinogen contaminations in the food chain, for example heavy metal ions, pesticides, acrylamide, and mycotoxins, have caused serious health problems. A major objective of food-safety research is the identification and prevention of exposure to these carcinogens, because of their impossible-to-reverse tumorigenic effects. However, carcinogen detection is difficult because of their trace-level presence in food. Thus, reliable and accurate separation and determination methods are essential to protect food safety and human health. This paper summarizes the state of the art in separation and determination methods for analyzing carcinogen contamination, especially the advances in biosensing methods. Furthermore, the application of promising technology including nanomaterials, imprinted polymers, and microdevices is detailed. Challenges and perspectives are also discussed.

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Acknowledgments

The research was supported by Project of the Ministry of Science and Technology of the People’s Republic of China (No. 2012BAD33B08).

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Biosystems Engineering, Zhejiang University, Hangzhou, 310058, China

    Zhanming Li & Yue Yu

  2. Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA

    Zhiliang Li

  3. Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310058, China

    Tao Wu

  4. Key Laboratory of Food Nutrition and Safety (Tianjin University of Science & Technology), Ministry of Education, Tianjin, 300457, China

    Tao Wu

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  1. Zhanming Li
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  2. Yue Yu
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  3. Zhiliang Li
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Correspondence to Tao Wu.

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Li, Z., Yu, Y., Li, Z. et al. A review of biosensing techniques for detection of trace carcinogen contamination in food products. Anal Bioanal Chem 407, 2711–2726 (2015). https://doi.org/10.1007/s00216-015-8530-8

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  • DOI: https://doi.org/10.1007/s00216-015-8530-8

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