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Analysis of the evolution of the detection limits of electrochemical DNA biosensors

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Abstract

In this paper we critically review detection limits of electrochemical DNA biosensors enabling DNA detection without target labelling. The review includes transduction principles and latest breakthroughs. To compare the efficiency of each type of electrochemical DNA biosensor, a simple DNA biosensors classification is established on the basis of the nature of the bio-electrochemical transduction.

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Authors and Affiliations

  1. Unité de Pharmacologie Chimique et Génétique et Imagerie, Chimie ParisTech, Ecole Nationale Supérieure de Chimie de Paris, Paris, France

    Mathieu Lazerges & Fethi Bedioui

  2. Unité de Pharmacologie Chimique et Génétique et Imagerie UMR 8151, CNRS, Paris, France

    Mathieu Lazerges & Fethi Bedioui

  3. Unité de Pharmacologie Chimique et Génétique et Imagerie, Université Paris Descartes, Paris, France

    Mathieu Lazerges & Fethi Bedioui

  4. Unité de Pharmacologie Chimique et Génétique et Imagerie (N° 1022), INSERM, Paris, France

    Mathieu Lazerges & Fethi Bedioui

Authors
  1. Mathieu Lazerges
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  2. Fethi Bedioui
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Correspondence to Mathieu Lazerges or Fethi Bedioui.

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Published in the topical collection Bioelectroanalysis with guest editors Nicolas Plumeré, Magdalena Gebala, and Wolfgang Schuhmann.

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Lazerges, M., Bedioui, F. Analysis of the evolution of the detection limits of electrochemical DNA biosensors. Anal Bioanal Chem 405, 3705–3714 (2013). https://doi.org/10.1007/s00216-012-6672-5

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  • DOI: https://doi.org/10.1007/s00216-012-6672-5

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