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Applications of microelectromagnetic traps

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Abstract

Microelectromagnetic traps (METs) have been used for almost two decades to manipulate magnetic fields. Different trap geometries have been shown to produce distinct magnetic fields and field gradients. Initially, microelectromagnetic traps were used mainly to separate and concentrate magnetic material at small scales. Recently such traps have been implemented for unique applications, for example filterless bioseparations, inductive heat generation, and biological detection. In this review, we describe recent reports in which MET geometry, current density, or external fields have been used. Descriptions of recent applications in which METs have been used to develop sensors, manipulate DNA, or block ion current are also provided.

Illustration of a magnetic particle trapped by the magnetic field of a microelectromagnet

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Abbreviations

DLVO:

Derjaguin–Landau–Verwey–Overbeek

IgG:

Immunoglobulin

MET(s):

Microelectromagnetic trap(s)

MP(s):

Magnetic particle(s)

PDMS:

Polydimethylsiloxane

SERRS:

Surface-enhanced resonance Raman scattering

SPAD:

Single photon avalanche diode

SPM:

Superparamagnetic

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Acknowledgements

The authors acknowledge the National Science Foundation (CHE-0847642) for support of our investigations in microelectromagnetics.

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Authors and Affiliations

  1. Department of Chemistry, Indiana University, Bloomington, IN, 47405, USA

    Joseph R. Basore & Lane A. Baker

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  1. Joseph R. Basore
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  2. Lane A. Baker
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Correspondence to Lane A. Baker.

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Footnote: Published in the special issue Young Investigators in Analytical and Bioanalytical Science with guest editors S. Daunert J. Bettmer, T. Hasegawa, Q. Wang and Y. Wei.

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Basore, J.R., Baker, L.A. Applications of microelectromagnetic traps. Anal Bioanal Chem 403, 2077–2088 (2012). https://doi.org/10.1007/s00216-012-6040-5

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