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Incidence of subsequent osteoporotic fractures after distal radius fractures and mortality of the subsequent distal radius fractures: a retrospective analysis of claims data of the Korea National Health Insurance Service

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Abstract

Summary

A better understanding of the features of subsequent fractures after distal radius fracture (DRF) is important for the prevention of further osteoporotic fractures. This study found that the cumulative incidence of subsequent osteoporotic fractures in South Korea increased over time and that the mortality rates of subsequent DRFs were lower than those of first-time DRFs.

Introduction

We examined the incidence of osteoporotic fractures following distal radius fractures (DRFs) and the mortality rate after subsequent DRFs using claims data from the Korea National Health Insurance (KNHI) Service.

Methods

We identified records for 41,417 patients with first-time DRFs in 2012. The occurrence of osteoporotic fractures of the spine, hip, wrist, and humerus at least 6 months after the index DRF was tracked through 2016. All fractures were identified by specific diagnosis and procedure codes. One-year mortality rates and standardized mortality ratios (SMRs) for initial and subsequent DRFs were calculated for all patients.

Results

The 4-year cumulative incidence of all subsequent osteoporotic fractures was 14.74% (6105/41,417; 9.47% in men, 15.9% in women). The number of associated subsequent fractures was 2850 for the spine (46.68%), 2271 for the wrist (37.2%), 708 for the hip (11.6%), and 276 for the humerus (4.52%). The cumulative mortality rate 1 year after the first-time and subsequent DRF was 1.47% and 0.71%, respectively, and the overall SMR was 1.48 (95% CI: 1.37–1.61) and 0.71 (95% CI: 0.42−1.21), respectively.

Conclusion

The cumulative incidence of osteoporotic fractures following DRFs increased over the study period and was higher among women. The cumulative mortality rates and SMRs of subsequent DRFs were lower than those of first-time DRFs at the 1-year follow-up. Given the increasing incidence rate of DRFs, the incidence of subsequent osteoporotic fractures may also increase.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea

    H.-S. Jung & Y.-C. Ha

  2. College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, Republic of Korea

    S. Jang

  3. Department of Endocrinology and Metabolism, School of Medicine, Kyung Hee University, Seoul, Republic of Korea

    H.-Y. Chung & S.Y. Park

  4. Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Republic of Korea

    H.-Y. Kim

  5. Department of Orthopaedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, Seongnam, Republic of Korea

    Y.-K. Lee

  6. Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, 59, Daesagwan-ro, Yongsan-gu, Seoul, 04401, Republic of Korea

    J.-H. Nho

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  1. H.-S. Jung
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  2. S. Jang
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  3. H.-Y. Chung
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  4. S.Y. Park
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  6. Y.-C. Ha
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  8. J.-H. Nho
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Correspondence to J.-H. Nho.

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The local Institutional Review Board approved this retrospective study (IRB No. WMCSB 201706-64). Informed consent was waived by the Board.

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Jung, HS., Jang, S., Chung, HY. et al. Incidence of subsequent osteoporotic fractures after distal radius fractures and mortality of the subsequent distal radius fractures: a retrospective analysis of claims data of the Korea National Health Insurance Service. Osteoporos Int 32, 293–299 (2021). https://doi.org/10.1007/s00198-020-05609-4

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  • DOI: https://doi.org/10.1007/s00198-020-05609-4

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