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Ultrasound measurement of bladder wall thickness in different forms of detrusor overactivity

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Abstract

Introduction and hypothesis

Aims of this study were to compare the ultrasound measurement of bladder wall thickness (BWT) in women with different urodynamic diagnosis and to correlate BWT to the different urodynamic findings of detrusor overactivity (DO).

Methods

Two hundred forty seven women with urinary symptoms have been prospectively enrolled. Urodynamics and transvaginal ultrasound BWT were performed. Patients were divided into four urodynamic subgroups. BWT of women with DO was compared with the BWT of any other subgroup.

Results

Women with DO had a BWT value significantly higher (p < 0.0001). A cut-off of 6.5 mm for BWT had a positive predictive value of 100% for all DO. We use ROC curves to analyze the BWT for urgency urinary incontinence (AUC 0.645 95% CI 0.57–0.72) and the BWT for “pure DO” (AUC 0.702 95% CI 0.64–0.76) and for “all DO” (AUC 0.704 95% CI 0.64–0.77) vs other urodynamic diagnoses.

Conclusions

The ultrasound BWT showed a highly significant association with DO. However, the performance of this test cannot currently replace urodynamic testing.

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Conflicts of interest

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Authors and Affiliations

  1. Dept. of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Piazza Biroldi, 1, Varese, 21100, Italy

    Maurizio Serati, Stefano Salvatore, Elena Cattoni, Antonella Cromi & Fabio Ghezzi

  2. Urogynecological Service, Obstetrics and Gynecology Unit, San Carlo Borromeo Hospital, Milan, Italy

    Marco Soligo

Authors
  1. Maurizio Serati
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  2. Stefano Salvatore
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  3. Elena Cattoni
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  4. Marco Soligo
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  5. Antonella Cromi
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  6. Fabio Ghezzi
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Corresponding author

Correspondence to Maurizio Serati.

Additional information

Trial Registration: ClinicalTrials.gov ID NCT01003457

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Serati, M., Salvatore, S., Cattoni, E. et al. Ultrasound measurement of bladder wall thickness in different forms of detrusor overactivity. Int Urogynecol J 21, 1405–1411 (2010). https://doi.org/10.1007/s00192-010-1194-1

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  • DOI: https://doi.org/10.1007/s00192-010-1194-1

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