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Do autologous blood transfusion systems reduce allogeneic blood transfusion in total knee arthroplasty?

  • Knee
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

Purpose

To study whether autologus blood transfusion systems reduce the requirement of allogneic blood transfusion in patients undergoing total knee arthroplasty.

Methods

A comprehensive search of the published literature with PubMed, Scopus and Science direct database was performed. The following search terms were used: (total knee replacement) OR (total knee arthroplasty) OR (TKA) AND (blood transfusion) OR (autologous transfusion) OR (autologous transfusion system). Using search syntax, a total of 748 search results were obtained (79 from PubMed, 586 from Science direct and 83 from Scopus). Twenty-one randomized control trials were included for this meta-analysis.

Results

The allogenic transfusion rate in autologus blood transfusion (study) group was significantly lower than the control group (28.4 and 53.5 %, respectively) (p value 0.0001, Relative risk: 0.5). The median units of allogenic blood transfused in study control group and control group were 0.1 (0.1–3.0) and 1.3 (0.3–2.6), respectively. The median hospital stay in study group was 9 (6.7–15.6) days and control group was 8.7 (6.6–16.7) days. The median cost incurred for blood transfusion per patient in study and control groups was 175 (85.7–260) and 254.7 (235–300) euros, respectively.

Conclusion

This meta-analysis demonstrates that the use of auto-transfusion systems is a cost-effective method to reduce the need for and quantity of allogenic transfusion in elective total knee arthroplasty.

Level of evidence

Level I.

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Author information

Authors and Affiliations

  1. L.T. Medical College, Sion, Mumbai, India

    Aditya Pawaskar

  2. Department of Orthopedics, Pramukswami Medical College, Anand, Gujrat, India

    Abhijeet Ashok Salunke & Subodhkumar Pathak

  3. D.Y. Patil Medical College, Mumbai, India

    Aashay Kekatpure

  4. Department of Orthopedics, National University Hospital, Singapore, Singapore

    Yongsheng Chen & Junhao Tan

  5. K.M. Nallasamy Hospital, Erode, Tamil Naidu, India

    G. I. Nambi

  6. J.J. Hospital, Mumbai, India

    Dhiraj Sonawane

Authors
  1. Aditya Pawaskar
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  2. Abhijeet Ashok Salunke
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Correspondence to Abhijeet Ashok Salunke.

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Pawaskar, A., Salunke, A.A., Kekatpure, A. et al. Do autologous blood transfusion systems reduce allogeneic blood transfusion in total knee arthroplasty?. Knee Surg Sports Traumatol Arthrosc 25, 2957–2966 (2017). https://doi.org/10.1007/s00167-016-4116-z

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  • DOI: https://doi.org/10.1007/s00167-016-4116-z

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