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A state of the art review on optimal practices to prevent, recognize, and manage complications associated with intravascular devices in the critically ill

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Abstract

Intravascular catheters are inserted into almost all critically ill patients. This review provides up-to-date insight into available knowledge on epidemiology and diagnosis of complications of central vein and arterial catheters in ICU. It discusses the optimal therapy of catheter-related infections and thrombosis. Prevention of complications is a multidisciplinary task that combines both improvement of the process of care and introduction of new technologies. We emphasize the main component of the prevention strategies that should be used in critical care and propose areas of future investigation in this field.

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Authors and Affiliations

  1. Université Paris Diderot/Hopital Bichat - Réanimation Medicale et des maladies infectieuses, Paris, 75018, France

    Jean-François Timsit

  2. UMR 1137 - IAME Team 5 – DeSCID: Decision Sciences in Infectious Diseases, Control and care Inserm/Univ Paris Diderot, Sorbonne Paris Cité, 75018, Paris, France

    Jean-François Timsit

  3. Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA

    Mark Rupp

  4. Department of Infection Control and Epidemiology, Nebraska Medicine, Omaha, NE, USA

    Mark Rupp

  5. Medicine Department, School of Medicine, Universidad Complutense de Madrid (UCM), Madrid, Spain

    Emilio Bouza

  6. Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    Emilio Bouza

  7. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain

    Emilio Bouza

  8. Division of Hospital Medicine, Department of Medicine, Patient Safety Enhancement Program and Center for Clinical Management Research, University of Michigan, Ann Arbor, MI, 48109, USA

    Vineet Chopra

  9. Department of Clinical Microbiology, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Mindelsohn Way, Edgbaston, Birmingham, B15 2GW, UK

    Tarja Kärpänen

  10. Department of Medicine, Royal Inland Hospital, Kamloops, BC, V2C 2T1, Canada

    Kevin Laupland

  11. Rede Institucional de Pesquisa e Inovação em Medicina Intensiva, Complexo Hospitalar Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil

    Thiago Lisboa

  12. Critical Care Department and Infection Control Committee, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil

    Thiago Lisboa

  13. Department of Medicine, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, USA

    Leonard Mermel

  14. Division of Infectious Diseases and Department of Epidemiology and Infection Control, Rhode Island Hospital, Providence, USA

    Leonard Mermel

  15. Service des Urgences-SAMU 86, CHU de Poitiers, Poitiers, France

    Olivier Mimoz

  16. Université de Poitiers, UFR de Médecine Pharmacie, Poitiers, France

    Olivier Mimoz

  17. INSERM U1070, Pharmacologie des Agents antiInfectieux, Poitiers, France

    Olivier Mimoz

  18. Department of Biostatistics and Clinical Research, Centre Hospitalier Universitaire (CHU), Caen, France

    Jean-Jacques Parienti

  19. INSERM Unité Mixte de Recherche Scientifique 1075 COMETE (N.T.) and EA4655 Risques Microbiens, Caen, France

    Jean-Jacques Parienti

  20. 4th Department of Internal Medicine, Attikon University General Hospital, Athens University School of Medicine, Athens, Greece

    Garyphalia Poulakou

  21. Service de Réanimation Médicale, Hôpital Gabriel Montpied, CHU de Clermont-Ferrand, BP 69, 63003, Clermont-Ferrand, Cedex 1, France

    Bertrand Souweine

  22. Université Clermont Auvergne, CNRS, LMGE, 63000, Clermont-Ferrand, France

    Bertrand Souweine

  23. Infection Control Program and WHO Collaborating Centre for Patient Safety, University of Geneva Hospitals, 4 rue Gabrielle Perret-Gentil, 1211, Geneva, Switzerland

    Walter Zingg

Authors
  1. Jean-François Timsit
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  2. Mark Rupp
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  3. Emilio Bouza
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  4. Vineet Chopra
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  5. Tarja Kärpänen
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  6. Kevin Laupland
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  7. Thiago Lisboa
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  8. Leonard Mermel
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  9. Olivier Mimoz
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  10. Jean-Jacques Parienti
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  11. Garyphalia Poulakou
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  12. Bertrand Souweine
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  13. Walter Zingg
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Corresponding author

Correspondence to Jean-François Timsit.

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Conflicts of interest

Dr. Chopra discloses receiving grant support from the Agency for Healthcare Quality and Research and honoraria for research talks as a visiting professor. Dr. Kärpänen has received honoraria to present at a symposium and attend an international conference supported by 3M. Since contributing to the manuscript, she has taken a Senior Clinical Research Specialist role at 3M Deutschland GmbH. Dr. Mermel has served as a consultant for Marvao Medical and Nobio. Dr. Mimoz received grant support from 3M and Carefusion-BD and honoraria for giving lectures from 3M and Carefusion-BD. Dr. Timsit received grant support from 3M and honoraria for giving lectures from 3M.

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Timsit, JF., Rupp, M., Bouza, E. et al. A state of the art review on optimal practices to prevent, recognize, and manage complications associated with intravascular devices in the critically ill. Intensive Care Med 44, 742–759 (2018). https://doi.org/10.1007/s00134-018-5212-y

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