Dear Editor
We read with interest the article by Ferrie et al. [1] on nutritional support in adult patients receiving extracorporeal membrane oxygenation (ECMO). The authors retrospectively audited 86 patients who received ECMO [venovenous (VV) or venoarterial (VA) mode] and fed using protocols that emphasize early enteral nutrition (EN). It is believed that the hemodynamic alterations which occur in these patients can lead to serious complications, such as mesenteric ischemia. The main finding of this elegant study is that early EN can be well tolerated in such patients (average 79.7 % of target nutrition). However, some obstacles to adequate nutrition were identified, such as the use of propofol for sedation, and 18 patients required parenteral support due to EN intolerance. Intolerance did not differ between ECMO modes.
We would like to discuss our recent findings on this subject as a complement to this study by Ferrie et al. [1]. We have recently reported a prospective case series of early EN in seven patients receiving VA ECMO for severe hemodynamic failure unresponsive to conventional therapies [2], as well as a prospective study involving 37 cardiac surgery patients with hemodynamic failure [3]. Although some differences are present in these two studies regarding the applied nutrition protocol and definition of nutritional goal, we came to the same main conclusion: early EN is possible and not associated with serious complications. However, we did note significant energy deficits, especially in patients with a long stay in the ICU (>14 days). Complications such as abdominal distention, diarrhea, and constipation were frequent (>25 % of included patients). These complications barely received any mention in the paper published by Ferrie et al. [1]. We would therefore like to ask the authors about their experience with energy balances using EN alone, as well as a more detailed description of EN-related complications.
Despite current recommendations regarding nutritional support in patients with hemodynamic failure [4], we agree with the authors that EN is possible in ECMO patients, always under proper medical supervision. Although controversial, we also consider that EN is also feasible in cardiac surgery patients with hemodynamic failure [5]. More studies are clearly warranted to confirm these findings.
References
Ferrie S, Herkes R, Forrest P (2013) Nutrition support during ECMO in adults a retrospective audit. Intensive Care Med. doi:10.1007/s00134-013-3053-2
Umezawa Makikado LD, Flordelís Lasierra JL, Pérez-Vela JL et al (2013) Early enteral nutrition in adults receiving venoarterial extracorporeal membrane oxygenation: an observational case series. JPEN 37:281–284
Flordelís Lasierra JL, Pérez-Vela JL, Umezawa Makikado LD et al (2013) Early enteral nutrition in postoperative cardiac surgery patients with haemodynamic failure. JPEN (in press)
Kreymanna KG, Berger MM, Deutzc NE et al (2006) ESPEN guidelines on enteral nutrition: intensive care. Clin Nutr 25:210–223
Thibault R, Pichard C, Wernermann J et al (2011) Cardiogenic shock and nutrition: safe? Intensive Care Med 37:35–45
Conflicts of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Umezawa Makikado, L.D., Flordelís Lasierra, J.L., Pérez-Vela, J.L. et al. Nutrition support during extracorporeal membrane oxygenation (ECMO) in adults. Intensive Care Med 39, 2240 (2013). https://doi.org/10.1007/s00134-013-3128-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00134-013-3128-0