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Determination of Selected Endocrine Disrupting Chemicals in Lake Van, Turkey

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Abstract

In the present study, we investigated the distribution of 17β-estradiol (E2), 17α-ethynylestradiol (EE2), alkylphenol ethoxylates (APEs) and organochlorine pesticides (DDE/DDT) in water and sediment samples in the Eastern Anatolia of Turkey, Lake Van, which is the largest soda lake in the world. The procedure consisted of solid phase extraction performed with OASIS HLB cartridges followed by non-competitive enzyme-linked immunosorbent assays (ELISA). The endocrine disrupting compounds E2, EE2, and DDT/DDE were detected in most of the lake samples with mean concentrations of 0.996 ± 0.304, 0.050 ± 0.022, and 0.749 ± 0.658 ng/L in water, respectively. Mean concentrations of E2, EE2 and DDT/DDE in sediment were 0.098 ± 0.053, 0.091 ± 0.072, and 1.281 ± 0.754 ng/g, respectively. APEs were not measured in the sediment samples. The EDCs levels in surface water and sediment samples were lower than that of other countries. The EDCs were also found in effluent and influent municipal sewage samples. Van city municipal wastewater treatment plant has no removal efficiency for EDCs.

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References

  • Ankley GT, Bencic DC, Breen MS, Collette TW, Conoly RB, Denslow ND, Edwards SW, Ekman DR, Garcia-Reyero N, Jensen KM, Lazorchak JM, Martinovic D, Miller DH, Perkins EJ, Orlando EF, Villeneuve DL, Wang RL, Watanabe KH (2009) Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action. Aquatic Toxicol 92:168–178

    Article  CAS  Google Scholar 

  • Ayas Z (2007) Review on DDT and its residues in Turkey`s wetlands. J Environ Biol 28(4):707–715

    CAS  Google Scholar 

  • Danulat E, Selçuk B (1992) Life history and environmental conditions of the anadromous Chalcalburnus tarichi (Cyprinidae) in the highly alkaline Lake Van, Eastern Anatolia Turkey. Arch Hidrobiol 126(1):105–125

    Google Scholar 

  • Desbrow C, Routledge EJ, Brighty GC, Sumpter JP, Waldock M (1998) Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening. Environ Sci Technol 32:1549–1558

    Article  CAS  Google Scholar 

  • Gutendorf B, Westendorf J (2001) Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthestic estrogens, phytoestrogens and xenoestrogens. Toxicology 166(1–2):79–89

    Article  CAS  Google Scholar 

  • Jobling S, Coey S, Whitmore JG, Kime DE, Van Look KJW, McAllister BG (2002) Wild intersex roach (Rutilus rutilus) have reduced fertility. Biol Reprod 67:515–524

    Article  CAS  Google Scholar 

  • Kime DE, Nash JP (1999) Gamete viability as an indicator of reproductive endocrine disruption in fish. Sci Total Environ 233:1–3

    Article  Google Scholar 

  • Kolpin DW, Furlong ET, Meyer MT, Thurman EM, Zaugg SD, Barber LB (2002) Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999–2000: a national reconnaissance. Environ Sci Technol 36(6):1202–1211

    Article  CAS  Google Scholar 

  • Laganà A, Bacaloni A, De Leva I, Faberi A, Fago G, Marino A (2004) Analytical methodologies for determining the occurrence of endocrine disrupting chemicals in sewage treatment plants and natural waters. Anal Chim Acta 501:79–88

    Article  Google Scholar 

  • Liu R, Zhou JL, Wilding A (2004) Simultaneous determination of endocrine disrupting phenolic compounds and steroids in water by solid-phase extraction-gas chromatography–mass spectrometry. J Chromatogr A 1022:179–189

    Article  CAS  Google Scholar 

  • Oğuz AR (2013) Environmental regulation of mitochondria-rich cells in Chalcalburnus tarichi (Pallas, 1811) during reproductive migration. J Membr Biol 3:183–188

    Google Scholar 

  • Oğuz AR, Ünal G (2011) The effects of 17α-ethynylestradiol, 4-nonylphenol and phenol red on vitellogenin synthesis in juvenile Chalcalburnus tarichi primary hepatocyte culture. Toxicol Ind Health 4:379–384

    Google Scholar 

  • Pojana G, Gomiero A, Jonkers N, Marcomini A (2007) Natural and synthetic endocrine disrupting compounds (EDCs) in water, sediment and biota of coastal lagoon. Environ Int 33:929–936

    Article  CAS  Google Scholar 

  • Rocha S, Domingues VF, Pinho C, Fernandes VC, Delerue-Matos C, Gamerio P (2013) Occurrence of bisphenol A, Estrone, 17β-estradiol and 17α-ethynylestradiol in Portuguese rivers. Bull Environ Contam Toxicol 90:73–78

    Article  CAS  Google Scholar 

  • Seki M, Yokota H, Maeda M, Tadokoro H, Kobayashi K (2003) Effects of 4-nonylphenol and 4-tert-octylphenol on sex differentiation and vitellogenin induction in medaka (Oryzias latipes). Environ Toxicol Chem 22(7):1507–1516

    CAS  Google Scholar 

  • Snedeker SM (2001) Pesticides and breast cancer risk: a review of DDT, DDE, and dieldrin. Environ Health Perspect 109:35–47

    CAS  Google Scholar 

  • Tanaka JN, Grizzle JM (2002) Effects of nonylphenol on the gonadal differentiation of the hermaphroditic fish, Rivilus marmoratus. Aquatic Toxicol 57:117–125

    Article  CAS  Google Scholar 

  • Ünal G, Türkoğlu V, Oğuz AR, Kaptaner B (2007) Gonadal histology and some biochemical characteristics of Chalcalburnus tarichi (Pallas, 1811) having abnormal gonads. Fish Physiol Biochem 33:153–165

    Article  Google Scholar 

  • Viganò L, Benfenati E, van Cauwenberge A, Eidem JK, Erratico C, Goksøyr A (2008) Estrogenicity profile and estrogenic compounds determined in river sediments by chemical analysis, ELISA and yeast assays. Chemosphere 73:1078–1089

    Article  Google Scholar 

  • Wang Y, Zhang Q, Lv J, Li A, Liu H, Li G, Jiang G (2007) Polybrominated diphenyl ethers and organochlorine pesticides in sewage sludge of wastewater treatment plants in China. Chemosphere 68:1683–1691

    Article  CAS  Google Scholar 

  • Wang L, Ying GG, Zhao JL, Liu S, Yang B, Zhou LJ, Tao R, Su HC (2011) Assessing estrogenic activity in surface water and sediment of the Liao River system in northest China using combined chemical and biological tools. Environ Pollut 159:148–156

    Article  CAS  Google Scholar 

  • Ying GG, Williams B, Kokana R (2002) Environmental fate of alkylphenols and alkylphenol ethoxylates—a review. Environ Int 28:215–226

    Article  CAS  Google Scholar 

  • Zaroogian G, Gardner G, Horowitz DB, Gutjahr-Gobell R, Haebler R, Mills L (2001) Effect of 17beta-estradiol, o, p′-DDT, octylphenol and p, p′-DDE on gonadal development and liver and kidney pathology in juvenile male summer flounder (Paralichthys dentatus). Aquat Toxicol 54(1–2):101–112

    Article  CAS  Google Scholar 

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Acknowledgments

This study was supported by Directorate of Scientific Research Projects of Yüzüncü Yıl University (Grant No. 2010-FED-B032). The authors kindly thank Van WWTP personnel for providing wastewater and sludge samples.

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Correspondence to Ahmet R. Oğuz.

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Oğuz, A.R., Kankaya, E. Determination of Selected Endocrine Disrupting Chemicals in Lake Van, Turkey. Bull Environ Contam Toxicol 91, 283–286 (2013). https://doi.org/10.1007/s00128-013-1036-1

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