Abstract
Studies show that different organisms used as bio-indicators have indicated several genotoxic and mutagenic effects of disinfected waters. In this study, the 96 h LC50 mean value of NaOCl for Orthrias angorae was calculated to be 0.5509 mg/L. The results showed that NaOCl is highly toxic to O. angorae specimens. Statistical analysis demonstrated a significant increase in micronuclei after the induction of 0.5 mg/L NaOCl concentration after 36 h. The same increase has been reported for 0.37 and 0.5 mg/L NaOCl concentrations after 72 h. Even though the MN frequency of 0.37 mg/L was similar after 36 and 72 h, only 72 h micronuclei frequency was statistically significant. The 72 h MN frequency of the negative control group was smaller than 36 h MN frequency of the negative control group. This discrepancy has led to 72 h MN frequency being statistically significant. MN frequency of 0.25 mg/L NaOCl concentration was insignificant when compared to negative test groups. The benzene treatment also caused a significant increase (p < 0.01) in the frequency of micronucleated erythrocytes.
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This research was supported by TUBITAK (105T319).
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Gül, S., Özkan, O., Nur, G. et al. Genotoxic Effects and LC50 Value of NaOCl on Orthrias angorae (Steindachner 1897). Bull Environ Contam Toxicol 80, 544–548 (2008). https://doi.org/10.1007/s00128-008-9404-y
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DOI: https://doi.org/10.1007/s00128-008-9404-y