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Symptomatic, functional and service utilization outcomes of migrants with a first episode of psychosis

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Abstract

Background

Certain migrant groups have been identified as being at increased risk of developing a psychotic disorder, but there is limited research on the outcomes for migrants who develop a first episode of psychosis (FEP). We investigated symptomatic outcomes (remission and relapse rates), functional outcomes (occupational status and relationships) and service utilization (hospital admission and engagement).

Methods

Young people, aged between 15 and 24, who presented with FEP to the Early Psychosis Prevention and Intervention Centre (EPPIC) at Orygen between 01.01.11 and 31.12.16 were included. Place of birth was recorded at the time of presentation. To determine remission, symptoms were scored at three-month intervals using the short-form Scale for the Assessment of Positive Symptoms.

Results

A total of 1220 young people presented with FEP over the six-year period (mean age = 19.6 ± 2.8). Of these, 58.1% were male and 24.0% were first-generation migrants. While there was no difference in overall rates of admission after presentation, migrants were more likely to have an involuntary admission after presentation (31.4% vs. 24.6%, aHR = 1.54, 95% CI [1.19, 2.01]) and this risk was greatest for African migrants (HR = 1.98, 95% C.I. [1.37, 2.86]. The rates of remission and relapse were similar in migrants and those born in Australia and there was no difference in functional outcomes, such as employment rates at follow-up.

Discussion

The outcomes for migrants who experience FEP appear to be largely similar to those for the Australian-born population. Our finding that a greater rate of involuntary admission for migrants at presentation supports existing literature and needs further exploration to improve clinical care.

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References

  1. Krstev H, Carbone S, Harrigan SM, Curry C, Elkins K, McGorry PD (2004) Early intervention in first-episode psychosis–the impact of a community development campaign. Soc Psychiatry Psychiatr Epidemiol 39(9):711–719. https://doi.org/10.1007/s00127-004-0798-5

    Article  PubMed  Google Scholar 

  2. Jackson HM, McGorry PD (2009) The recognition and management of early psychosis. A preventive approach, 2nd edn. Cambridge University Press, Cambridge

    Book  Google Scholar 

  3. Selten JP, van der Ven E, Termorshuizen F (2019) Migration and psychosis: a meta-analysis of incidence studies. Psychol Med. https://doi.org/10.1017/s0033291719000035

    Article  PubMed  PubMed Central  Google Scholar 

  4. Satinsky E, Fuhr DC, Woodward A, Sondorp E, Roberts B (2019) Mental health care utilisation and access among refugees and asylum seekers in Europe: a systematic review. Health Policy 123(9):851–863. https://doi.org/10.1016/j.healthpol.2019.02.007

    Article  PubMed  Google Scholar 

  5. Kiselev N, Pfaltz M, Haas F, Schick M, Kappen M, Sijbrandij M, De Graaff AM, Bird M, Hansen P, Ventevogel P, Fuhr DC, Schnyder U, Morina N (2020) Structural and socio-cultural barriers to accessing mental healthcare among Syrian refugees and asylum seekers in Switzerland. Eur J Psychotraumatol 11(1):16. https://doi.org/10.1080/20008198.2020.1717825

    Article  Google Scholar 

  6. Maguire J, Sizer H, Mifsud N, O’Donoghue B (2020) Outcomes for migrants with a first episode of psychosis: a systematic review. Schizophr Res. https://doi.org/10.1016/j.schres.2020.05.048

    Article  PubMed  Google Scholar 

  7. Tarricone I, Morgan C, Boydell J, Panigada S, Morigi R, Braca M, Sutti E, Boldri P, Di Forti M, Murray RM, Berardi D (2017) Occupation and first episode psychosis in Northern Italy: better outcomes for migrants. Early Intervention in Psychiatry 11(6):522–525

    Article  Google Scholar 

  8. Abdel-Baki A, Ouellet-Plamondon C, Medrano S, Nicole L, Rousseau C (2018) Immigrants’ outcome after a first-episode psychosis. Early Intervention in Psychiatry 12(2):193–201

    Article  Google Scholar 

  9. Callan AF (1996) Schizophrenia in Afro-Caribbean immigrants. J R Soc Med 89(5):253–256

    Article  CAS  Google Scholar 

  10. Rodrigues R, MacDougall AG, Zou G, Lebenbaum M, Kurdyak P, Li L, Shariff SZ, Anderson KK (2019) Involuntary hospitalization among young people with early psychosis: a population-based study using health administrative data. Schizophr Res 208:276

    Article  Google Scholar 

  11. Anderson KK, Rodrigues R, MacDougall A (2018) Risk of involuntary admission among firstgeneration ethnic minority groups with first episode psychosis: estimates from population based health administrative data. Early Intervention in Psychiatry 12(Supplement 1):150

    Google Scholar 

  12. Zandi T, Havenaar JM, Laan W, Kahn RS, van den Brink W (2011) Predictive validity of a culturally informed diagnosis of schizophrenia: a 30 month follow-up study with first episode psychosis. Schizophr Res 133(1–3):29–35

    Article  Google Scholar 

  13. Berg A, Barrett E, Melle I (2014) Insight over time in first generation immigrants with first episode psychosis. Early Intervention in Psychiatry 1:104

    Google Scholar 

  14. Golay P, Baumann P, Jaton L, Restellini R, Mebdouhi N, Conus P (2018) Migration in patients with early psychosis is a two-sided coin: findings from a three year prospective study. Early Intervention in Psychiatry 12(Supplement 1):9

    Google Scholar 

  15. Stouten LH, Veling W, Laan W, Van der Gaag M (2019) Psychopathology, cognition and outcome in Dutch and immigrant first-episode psychosis patients. Early Intervention Psychiatry 13(3):646–656

    Article  Google Scholar 

  16. Termorshuizen F, Wierdsma AI, Visser E, Drukker M, Sytema S, Laan W, Smeets HM, Selten JP (2012) Psychosis and suicide risk by ethnic origin and history of migration in the Netherlands. Schizophr Res 138(2–3):268–273

    Article  Google Scholar 

  17. Maraj A, Veru F, Morrison L, Joober R, Malla A, Iyer S, Shah J (2018) Disengagement in immigrant groups receiving services for a first episode of psychosis. Schizophr Res 193:399–405

    Article  Google Scholar 

  18. Ouellet-Plamondon C, Rousseau C, Nicole L, Abdel-Baki A (2015) Engaging immigrants in early psychosis treatment: a clinical challenge. Psychiatric Services 66(7):757–759

    Article  Google Scholar 

  19. Rodrigues R, MacDougall AG, Zou G, Lebenbaum M, Kurdyak P, Li L, Shariff SZ, Anderson KK (2019) Risk of involuntary admission among first-generation ethnic minority groups with early psychosis: a retrospective cohort study using health administrative data. Epidemiol Psychiatric Sci. https://doi.org/10.1017/s2045796019000556

    Article  Google Scholar 

  20. O’Donoghue B, Downey L, Eaton S, Mifsud N, Kirkbride JB, McGorry P (2020) Risk of psychotic disorders in migrants to Australia. Psychol Med. https://doi.org/10.1017/s0033291719004100

    Article  PubMed  Google Scholar 

  21. Eaton S, Harrap B, Downey L, Thien K, Bowtell M, Bardell-Williams M, Ratheesh A, McGorry P, O’Donoghue B (2019) Incidence of treated first episode psychosis from an Australian early intervention service and its association with neighbourhood characteristics. Schizophr Res 209:206–211. https://doi.org/10.1016/j.schres.2019.04.017

    Article  PubMed  Google Scholar 

  22. Kim DJ, Brown E, Reynolds S, Geros H, Sizer H, Tindall R, McGorry P, O’Donoghue B (2019) The rates and determinants of disengagement and subsequent re-engagement in young people with first-episode psychosis. Soc Psychiatry Psychiatr Epidemiol 54(8):945–953. https://doi.org/10.1007/s00127-019-01698-7

    Article  PubMed  Google Scholar 

  23. Wing JK, Beevor AS, Curtis RH, Park SB, Hadden S, Burns A (1998) Health of the Nation Outcome Scales (HoNOS). Research and development. The British Journal Psychiatry Journal Of Mental Science 172:11–18

    Article  CAS  Google Scholar 

  24. Preti A, Pisano A, Cascio MT, Galvan F, Monzani E, Meneghelli A, Cocchi A (2012) Validation of the Health of the Nation Outcome Scales as a routine measure of outcome in early intervention programmes. Early Intervention in Psychiatry 6(4):423–431. https://doi.org/10.1111/j.1751-7893.2011.00329.x

    Article  PubMed  Google Scholar 

  25. Barnett P, Mackay E, Matthews H, Gate R, Greenwood H, Ariyo K, Bhui K, Halvorsrud K, Pilling S, Smith S (2019) Ethnic variations in compulsory detention under the Mental Health Act: a systematic review and meta-analysis of international data. Lancet Psychiatry 6(4):305–317. https://doi.org/10.1016/s2215-0366(19)30027-6

    Article  PubMed  PubMed Central  Google Scholar 

  26. Morgan C, Mallett R, Hutchinson G, Bagalkote H, Morgan K, Fearon P, Dazzan P, Boydell J, McKenzie K, Harrison G, Murray R, Jones P, Craig T, Leff J (2005) Pathways to care and ethnicity. 1: sample characteristics and compulsory admission. Report from the AESOP study. British J Psychiatry J Mental Sci 186:281–289

    Article  CAS  Google Scholar 

  27. Szmukler GI, Bird AS, Button EJ (1981) Compulsory admissions in a London borough: I. Social and clinical features and a follow-up. Psychol Med 11(3):617–636

    Article  CAS  Google Scholar 

  28. Morgan C, Mallett R, Hutchinson G, Bagalkote H, Morgan K, Fearon P, Dazzan P, Boydell J, McKenzie K, Harrison G, Murray R, Jones P, Craig T, Leff J (2005) Pathways to care and ethnicity. 2: source of referral and help-seeking. Report from the AESOP study. British J Psychiatry J Mental Sci 186:290–296

    Article  CAS  Google Scholar 

  29. Bourque F, van der Ven E, Malla A (2011) A meta-analysis of the risk for psychotic disorders among first- and second-generation immigrants. PsycholMed 41(5):897–910

    CAS  Google Scholar 

  30. Baudin G, Godin O, Lajnef M, Aouizerate B, Berna F, Brunel L, Capdevielle D, Chereau I, Dorey JM, Dubertret C, Dubreucq J, Faget C, Fond G, Gabayet F, Laouamri H, Lancon C, Le Strat Y, Tronche AM, Misdrahi D, Rey R, Passerieux C, Schandrin A, Urbach M, Vidalhet P, Llorca PM, Schürhoff F (2016) Differential effects of childhood trauma and cannabis use disorders in patients suffering from schizophrenia. Schizophr Res 175(1–3):161–167. https://doi.org/10.1016/j.schres.2016.04.042

    Article  CAS  PubMed  Google Scholar 

  31. Schoeler T, Petros N, Di Forti M, Klamerus E, Foglia E, Murray R, Bhattacharyya S (2017) Poor medication adherence and risk of relapse associated with continued cannabis use in patients with first-episode psychosis: a prospective analysis. Lancet Psychiatry 4(8):627–633. https://doi.org/10.1016/s2215-0366(17)30233-x

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Brian O’Donoghue.

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Maguire, J., Mifsud, N., Seiler, N. et al. Symptomatic, functional and service utilization outcomes of migrants with a first episode of psychosis. Soc Psychiatry Psychiatr Epidemiol 56, 1389–1397 (2021). https://doi.org/10.1007/s00127-020-02011-7

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