Zusammenfassung
Hintergrund
Schlaf ist ein Zustand, der die Konsolidierung kürzlich erworbener Gedächtnisinhalte optimiert. Daher könnten Schlafstörungen zu Gedächtnisverminderungen bei psychiatrischen Erkrankungen wie der Depression oder der Schizophrenie beitragen.
Methode
Dieser Beitrag gibt einen Überblick über die aktuelle Forschung zum Thema Schlaf und Gedächtnis mit dem Fokus auf psychiatrische Erkrankungen.
Ergebnisse und Schlussfolgerungen
Störungen in der Schlafstruktur sind assoziiert mit bestimmten Gedächtnisdefiziten bei Patienten mit unterschiedlichen psychischen Erkrankungen. Wirksame Behandlungen von Schlafverminderungen sollten nicht nur den Schlaf an sich, sondern auch die assoziierten Gedächtniseinschränkungen verbessern. Erste Beispiele dafür werden genannt.
Summary
Background
Sleep has been identified as a state that optimizes the consolidation of newly acquired information in the memory. Sleep disturbances might essentially contribute to memory impairment in relevant psychiatric disorders, such as major depression and schizophrenia.
Methods
This article provides a brief review of the latest research results on sleep and its association with memory consolidation.
Results and conclusion
Specific disturbances of sleep structure are associated with particular memory deficits in psychiatric patients. Effective treatment of sleep disorders should not only improve signs of sleep but should also heal associated memory impairments.
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Danksagung
Wir danken der DFG für die Förderung wesentlicher Studien, insbesondere über den SFB 654 Plastizität und Schlaf TP A9 (R.G.) sowie VO 542/9-1 (C.N.) und SNF PP00P1_133685 (B.R.).
Einhaltung ethischer Richtlinien
Interessenkonflikt. R. Göder und B. Rasch geben an, dass kein Interessenkonflikt besteht. C. Nissen hat Vortragshonorare von den Firmen Servier und Novartis erhalten. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
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Göder, R., Nissen, C. & Rasch, B. Schlaf, Lernen und Gedächtnis: Relevanz für Psychiatrie und Psychotherapie. Nervenarzt 85, 50–56 (2014). https://doi.org/10.1007/s00115-013-3894-5
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DOI: https://doi.org/10.1007/s00115-013-3894-5